Protein and Peptide Letters 2004-Apr
Vatairea macrocarpa lectin induces paw edema with leukocyte infiltration.
Vain rekisteröityneet käyttäjät voivat kääntää artikkeleita
Kirjaudu sisään Rekisteröidy
Linkki tallennetaan leikepöydälle
Avainsanat
Abstrakti
A lectin from Vatairea macrocarpa (Vmac) seeds was investigated in a model of paw edema in rats and the possible involvement of leukocytes. Vmac (200 and 400 microg/paw, s.c.) induced a significant time- and dose-dependent paw edema, with leukocyte infiltration, which was drastically reduced in leukopaenic animals. These data suggest a pro-inflammatory effect for this lectin that is dependent on the presence of leukocytes.
