Antioxidant Effect of Aged Garlic Extract
Mots clés
Abstrait
Rendez-vous
| Dernière vérification: | 07/31/2015 |
| Première soumission: | 12/17/2013 |
| Inscription estimée soumise: | 12/17/2013 |
| Première publication: | 12/23/2013 |
| Dernière mise à jour soumise: | 08/16/2015 |
| Dernière mise à jour publiée: | 08/18/2015 |
| Date de début réelle de l'étude: | 10/31/2013 |
| Date d'achèvement primaire estimée: | 03/31/2015 |
| Date estimée d'achèvement de l'étude: | 03/31/2015 |
Condition ou maladie
Intervention / traitement
Dietary Supplement: Placebo
Dietary Supplement: Aged garlic extract
Phase
Groupes d'armes
| Bras | Intervention / traitement |
|---|---|
| Placebo Comparator: Placebo Smoker subjects take 6 capsules once a day for 4 weeks. | Dietary Supplement: Placebo |
| Experimental: Aged garlic extract Smoker subjects take 1.5 g of aged garlic extract in 6 capsules once a day for 4 weeks. | Dietary Supplement: Aged garlic extract |
| No Intervention: Non-smoker Oxidative status in non-smoker |
Critère d'éligibilité
| Âges éligibles aux études | 40 Years À 40 Years |
| Sexes éligibles à l'étude | Male |
| Accepte les bénévoles en santé | Oui |
| Critères | Inclusion Criteria: - Smoking (at least 20 cigarettes per day) or non-smoking (more than 20 years) Exclusion Criteria: - Under medication for chronic disease - Garlic allergy - Engaging in vigorous exercise - Taking drugs or functional food that may possess antioxidant property - Participation in any clinical trial within 90 days of the commencement of the trial - Renal or hepatic dysfunction - Heart disease |
Résultat
Mesures des résultats primaires
1. Urinary 8-hydroxydeoxyguanosine (8-OHdG) [Every 4 weeks (Overall 12 weeks)]
Mesures des résultats secondaires
1. High sensitive CRP [Every 4 weeks (Overall 12 weeks)]
2. Blood pressure [Every 4 weeks (Overall 12 weeks)]
3. Indices of the second derivative of photoplethysmogram (SDPTG) [Every 4 weeks (Overall 12 weeks)]
