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13 résultats
Prolonged cholestasis after ajmaline-induced acute hepatitis.
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We report the cases of 3 patients in whom ajmaline-induced acute hepatitis was followed by anicteric cholestasis persisting for more than 1 year after cessation of administration of the drug. Ajmaline was given for 8-16 days before the onset of acute hepatitis. Jaundice was preceded by fever, chills
Cholestatic hepatitis after diagnostic ajmaline challenge.
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We report a cholestatic hepatitis in an elderly woman after ajmaline challenge during electrophysiological testing for Brugada syndrome. No other medication was reported in the previous 6 months of the onset of jaundice. Liver biopsy showed a cholestatic hepatitis with mild biliary damage. Liver
[Ajmaline-induced hepatitis. A case report with ultrastructural study].
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The authors report the case of a patient with ajmaline hepatitis. The clinical presentation suggested angiocholitis; serum bilirubin concentration and the activity of alkaline phosphatase were markedly increased; serum transaminase activity was moderately increased; the prothrombin time remained
[Hepatitis due to ajmaline. Report of cases and review of the literature].
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The authors report the cases of 4 patients with jaundice following the administration of ajmaline. The disease had a pseudo- angiocholitic onset with fever, chills and pruritus in the 4 patients and abdominal pains in 2 patients. Serum transaminase activity and serum alkaline phosphatase activity
[Prolonged hepatitis due to ajmaline--description of a case and review of the literature].
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A 60 years old woman was admitted for jaundice and fever which appeared after a treatment with ajmaline-butabarbital for two-weeks. Abdominal ultrasound examination and endoscopic retrograde cholangiography were normal. Mitochondrial antibodies were absent. Jaundice persisted for three years,
[Ajmaline induced hepatitis in Denmark].
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[Diagnostic difficulties in ajmaline-induced hepatitis].
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'Intrahepatic cholestatic hepatitis following diagnostic ajmaline challenge'.
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[Agranulocytosis and cholestatic hepatitis during treatment with ajmaline].
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[Cholestatic hepatitis due to ajmaline. Lymphatic congestion of the liver. Recovery after spironolactone].
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[Cholestatic hepatitis and lymphatic liver congestion caused by ajmaline. Resolution of complete cholestasis with spironolactone?].
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Drug-induced hepatitis associated with anticytoplasmic organelle autoantibodies.
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A study from five hepatology units documenting 157 cases of drug-induced hepatitis and a second study from a laboratory of immunology which tested more than 100,000 sera permitted us to establish the frequency of antiorganelle antibodies and their diagnostic value in drug-induced hepatitis. In
[Acute anicteric hepatitis and intrahepatic cholestasis caused by administration of prajmalium bitartrate (Neo-Gilurytmal)].
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The authors draw attention to a serious drug response to the derivative of the alkaloid ajmaline prajmalium (Neo-Gilurytmal, Giulini-GFR) which causes impairment of liver functions of various grades as a result of intrahepatic cholestasis. They draw attention to the necessity of a careful
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