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artemisia integrifolia/crise épileptique
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The origin of epileptiform seizures caused by oil of Artemisia caerulescens L.
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Central properties of the essential oil and the crude ethanol extract from aerial parts of Artemisia annua L.
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The present study evaluated the central activity of the essential oil and the ethanolic extract from Artemisia annua L. in animals as a part of a psychopharmacological screening of this plant. The extract was prepared with fresh leaves in ethanol (AEE) and the essential oil (AEO) was obtained by
Vincent van Gogh and the thujone connection.
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During his last two years Vincent van Gogh experienced fits with hallucinations that have been attributed to a congenital psychosis. But the artist admitted to episodes of heavy drinking that were amply confirmed by colleagues and there is good evidence to indicate that addiction to absinthe
Identification and Quantification of Thujone in a Case of Poisoning Due to Repeated Ingestion of an Infusion of Artemisia Vulgaris L.
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Plants of the Artemisia genus are used worldwide as ingredients of botanical preparations. This paper describes the case of a 49-year-old man admitted to the emergency room at a Zurich hospital in a manic state after the ingestion of 1 L of an infusion of Artemisia vulgaris. Two monoterpenic
The choice of thujone as drug for diabetes.
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The use of thujone, a monoterpene ketone often present in sage (Salvia officinalis L.) or wormwood (Artemisia absinthium L.), for the treatment of diabetes mellitus was recently suggested in a study published in this journal. Evidence was based on the findings obtained in a diabetic rat model. After
Evaluation of the central properties of Artemisia verlotorum.
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The anticonvulsive activity of the crude hydroalcoholic extract (HE) of Artemisia verlotorum (Compositae) was analysed as a part of a psychopharmacological screening of this plant. High doses of HE (2 g/kg) prevented the onset of electroshock (75 mA, 60 Hz) and pentylenetetrazole-induced (75 mg/kg
Psychopharmacological effects of Artemisia copa aqueous extract in mice.
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OBJECTIVE
To evaluate the aqueous extract from aerial parts of Artemisia copa Phil. (Asteraceae) administered orallyfor its psychopharmacological activities in several experimental models.
METHODS
The extract was administered p.o. in Swiss albino mice and tested on pentobarbital-induced hypnosis,
Differential effects of orally versus parenterally administered qinghaosu derivative artemether in dogs.
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Artemether (AM) is an antimalarial drug derived from artemisinin (Qinghaosu), an extract of the herb Artemisia annua L., sweet wormwood. Its antiparasitic effect is that of a schizontocide and is explained by rapid uptake by parasitized erythrocytes and interaction with a component of hemoglobin
Wormwood (Artemisia absinthium L.)--a curious plant with both neurotoxic and neuroprotective properties?
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The medical use of the wormwood plant Artemisia absinthium L. dates back to at least Roman times, while during the last century this tradition was seemingly on the decline due to fears of absinthism, a syndrome allegedly caused by the wormwood-flavoured spirit absinthe and more specifically as a
Bioactive Compounds, Pharmacological Actions, and Pharmacokinetics of Wormwood ( Artemisia absinthium)
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Plants have been used since ancient times to cure certain infectious diseases, and some of them are now standard treatments for several diseases. Due to the side effects and resistance of pathogenic microorganisms to antibiotics and most drugs on the market, a great deal of attention has been paid
GABA-A Receptor Modulation and Anticonvulsant, Anxiolytic, and Antidepressant Activities of Constituents from Artemisia indica Linn.
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Artemisia indica, also known as "Mugwort," has been widely used in traditional medicines. However, few studies have investigated the effects of nonvolatile components of Artemisia indica on central nervous system's function. Fractionation of Artemisia indica led to the isolation of carnosol, ursolic
Thujone--cause of absinthism?
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Habitual abuse of the wormwood spirit absinthe was described in the 19th and 20th centuries as a cause for the mental disorder "absinthism" including the symptoms hallucinations, sleeplessness and convulsions. A controversial discussion is going on if thujone, a characteristic component of the
Anticonvulsant activity and chemical composition of Artemisia dracunculus L. essential oil.
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Artemisia dracunculus L. (Asteraceae) has been used orally as an antiepileptic remedy in Iranian folkloric medicine. The anticonvulsant potential and composition of the essential oil obtained from the aerial parts of the plant were assessed in this study. The essential oil exerted dose- and
Absinthism: a fictitious 19th century syndrome with present impact.
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Absinthe, a bitter spirit containing wormwood (Artemisia absinthium L.), was banned at the beginning of the 20th century as consequence of its supposed unique adverse effects. After nearly century-long prohibition, absinthe has seen a resurgence after recent de-restriction in many European
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