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A phase I/II study of intraperitoneally administered doxorubicin entrapped in cardiolipin liposomes in patients with ovarian cancer.

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A phase I and II clinical trial of intraperitoneally administered liposome-encapsulated doxorubicin in patients with advanced ovarian cancer is being evaluated. Doxyrubicin liposomes were prepared with cardiolipin, phosphatidyl choline, cholesterol, and sterarylamine and sized by flow cytometry

Histopathology of catastrophic antiphospholipid syndrome-associated nephropathy in a SLE patient without concurrent lupus nephritis.

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A 35-year-old African American male with a history of seizures, presented with nausea, vomiting, abdominal pain, thrombocytopenia (platelet count of 48,000) and acute renal failure (BUN/creatinine - 30/5.6). Urinalysis showed mild proteinuria and microscopic hematuria. He was diagnosed with systemic

[Renovascular hypertension associated with antiphospholipid antibodies in a woman with systemic lupus erythematosus].

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Systemic lupus erythematosus (SLE) patients, especially those with antiphospholipid antibodies, have a high incidence of arterial and venous thrombotic manifestations. However, renovascular hypertension (RVH) has been rarely reported in these patients. We describe here a 49-year-old female with

Mesenteric and portal venous obstruction associated with primary antiphospholipid antibody syndrome.

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A 58-year-old Korean man who had a past history of appendicitis, superior mesenteric vein thrombosis and intestinal obstruction presented 7 years later suffering from colicky right upper quadrant pain, epigastric discomfort after fatty meals, nausea and vomiting. He was found to have thrombosis of

Is there an ethnic difference in the prevalence of lupus cystitis? A report of six cases.

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Lupus cystitis was rare but frequently resulted in obstructive uropathy and had a strong association with gastrointestinal (GI) symptoms. We treated six patients with systemic lupus erythematosus (SLE) and obstructive uropathy from January 1996 to December 2001 in a university hospital. Evidence of

Esophageal abnormalities in juvenile localized scleroderma: is it associated with other extracutaneous manifestations?

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To assess esophageal involvement (EI) in juvenile localized scleroderma (JLS) population and the possible association between this gastrointestinal manifestation and demographic data, clinical features, laboratory exams, treatments and outcomes. For a period of 30 years, 5881 patients with rheumatic

[Bilateral papillary edema in cerebrospinal syphilis].

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BACKGROUND Nowadays luetic infections are rarely seen by ophthalmologists. We report on an immunocompetent ophthalmologically asymptomatic patient with bilateral papilledema due to perineuritis optici in lues cerebrospinalis. METHODS A 47-year old female patient presented with presbyopic complaints.

Migraine-like headache in cerebral venous sinus thrombosis.

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A 20-year-old female, university student presented with severe, throbbing, unilateral headache, nausea and vomiting that started 2 days ago. The pain was aggravated with physical activity and she had photophobia. She had been taking contraceptive pills due to polycystic ovary for 3 months. Cranial

Adrenal insufficiency complicated with antiphospholipid syndrome (APS).

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We describe a 69-year-old woman with bilateral adrenal hemorrhage complicated with antiphospholipid syndrome (APS). She was hospitalized with nausea and vomiting in September 2003. Laboratory data demonstrated hyponatremia, hypoglycemia and prolongation of activated partial thromboplastin time
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