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dimethyl sulfide/fibrose
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Mercaptans and dimethyl sulfide in the breath of patients with cirrhosis of the liver. Effect of feeding methionine.
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Clinical application of breath analysis for dimethyl sulfide following ingestion of DL-methionine.
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After overnight-fasting, the concentration of dimethyl sulfide in expired alveolar gas (alv-DMS) was determined serially following ingestion of 2 g of DL-methionine in normal subjects and patients with liver diseases. Alv-DMS rose to a peak in 30 to 90 min, declined markedly within 3 h, and then
Evaluation of volatile sulfur compounds in the expired alveolar gas in patients with liver cirrhosis.
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Trace amounts of volatile sulfur compounds were determined in the expired alveolar gas by gas chromatography. Among these sulfur containing substances, methyl mercaptan and dimethyl sulfide were quantitatively analyzed in 116 subjects; 53 normal, 13 acute hepatitis, 11 chronic hepatitis, 20 hepatic
Stable isotope profiles reveal active production of VOCs from human-associated microbes.
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Volatile organic compounds (VOCs) measured from exhaled breath have great promise for the diagnosis of bacterial infections. However, determining human or microbial origin of VOCs detected in breath remains a great challenge. For example, the microbial fermentation product 2,3-butanedione was
Analysis of breath volatile organic compounds in children with chronic liver disease compared to healthy controls.
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Breath testing is increasingly being used as a non-invasive diagnostic tool for disease states across medicine. The purpose of this study was to compare the levels of volatile organic compounds (VOCs) as measured by mass spectrometry in healthy children and children with chronic liver disease (CLD).
Volatomic analysis identifies compounds that can stratify non-alcoholic fatty liver disease
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Background & aims: Analysis of volatile organic compounds (VOCs) in exhaled breath, 'volatomics', provides opportunities for non-invasive biomarker discovery and novel mechanistic insights into a variety of diseases. The purpose of
GC-MS analysis of breath odor compounds in liver patients.
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BACKGROUND
Liver diseases can cause a sweet, musty aroma of the breath, called fetor hepaticus. Even in a stage of cirrhosis, the disease can be asymptomatic for many years. Breath analysis might be helpful to detect occult liver pathology.
OBJECTIVE
This study examined whether specific breath odor
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