4 résultats
OBJECTIVE
In the present study we investigated the antinociceptive, anti-inflammatory and antipyretic effects of 7-hydroxycoumarin (7-HC) in animal models.
METHODS
The effects of oral 7-HC were tested against acetic acid-induced writhing, formalin test, tail flick test, complete Freund's adjuvant
We previously demonstrated that 7-hydroxycoumarin (7HC) was effective in reducing proinflammatory cytokine production in lipopolysaccharide-exposed macrophage-like P388D1 cells and fever production by suppressing the increase in interleukin (IL)-1alpha production in an influenza virus-intranasal
Extracts from the roots of Peucedanum ostruthium (L.) Koch were investigated for their antiphlogistic and antipyretic effects as well as for their influence on arachidonic acid metabolism. On carrageenan-induced rat paw edema, oral administration of 10% ethanolic extracts led to a marked inhibition