oral administration of 0.28 mg of lutein in two doses: within 6 hours (hrs) after birth and at 36 hrs of life

oral administration of 0.28 mg of vehicle (0.5 mL of 5% glucose solution) in two doses: within 6 hours (hrs) after birth and at 36 hrs of life

Infant, Newborn, Diseases

Other Lipid Storage Disorders

After randomisation, the infant received orally a total dose of 0.28 mg of lutein in two doses: within 6 hours after birth and at 36 hours of life

Lutein drops

After randomization, newborns received 0.5 mL of 5% glucose solution in two doses: within 6 hours (hrs) after birth and at 36 hrs of life.

Glucose drops

AOUS

Evaluation of Antioxidant Activity of Oral Lutein in Preterm and Term Newborn

Giuseppe Buonocore

Professor

University of Siena

Careggi Hospital

sildenafil administration perioperative to renal transplant

Renal Transplant Failure

The intervention group will receive standard care in all capacities with the exception of sildenafil administration. The first dose (50mg) will be given 1-hour prior to the surgery. Patients will be given Sildenafil twice daily up to 3 days post-transplant.

Sildenafil

Vancouver General Hospital

PDE5i Use in Renal Transplant Recipients

perioperative safety of sildenafil administration to renal transplant

Christopher Nguan

associate professor

University of British Columbia

Macular Degeneration

Aspirin

Beta-Carotene

Randomized Trial of Beta-Carotene and Macular Degeneration

National Eye Institute (NEI)

Patients will receive a total intravenous melatonin dose of 11.61 mg (aproximately 166 μg/kg).

Patients will receive the same dose of placebo.

Reperfusion Injury, Myocardial

Patients will receive a total intravenous melatonin (Helsinn Chemical Co, Biasca, Switzerland) dose of 11.61 mg (aproximately 166 μg/kg). The dose will be distributed in a volume of 500 ml of an isotonic and sterile solution of 100 μM melatonin during 150 min with a drip rate of 4.2 ml/min.
The temporal distribution of perfusion will be: 30 min previous to percutaneous revascularization and remainder doses in a subsequent 120 min (1 h during the angioplasty +60 min post-intervention).

melatonin (Helsinn Chemical Co, Biasca, Switzerland)

The temporal distribution of perfusion will be: 30 min previous to percutaneous revascularization and remainder doses in a subsequent 120 min (1 h during the angioplasty +60 min post-intervention).

Placebos

PLA General Hospital

Effects of Melatonin on Reperfusion Injury

Effects of Melatonin on Reperfusion Injury in Patients With ST-segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

The salvage index measured by cardiac magnetic resonance

The final infarct size measured by cardiac magnetic resonance

recurrent myocardial infarction, recurrent angina, revascularization, heart failure, cardiac death.

Chen Wei Ren, MD

doctor

Chinese PLA General Hospital

Patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

Cataract

Lens Opacities

500 milligrams vitamin C; 400 IUs vitamin E; 15 milligrams beta-carotene

Antioxidants

80 milligrams zinc oxide; 2 milligrams of cupric oxide

Zinc

500 milligrams vitamin C; 400 IUs vitamin E; 15 milligrams beta-carotene; 80 milligrams zinc oxide; 2 milligrams of cupric oxide

iris/antioxydant

Evaluation of Antioxidant Activity of Oral Lutein in Preterm and Term Newborn

PDE5i Use in Renal Transplant Recipients

Randomized Trial of Beta-Carotene and Macular Degeneration

Effects of Melatonin on Reperfusion Injury

Age-Related Eye Disease Study (AREDS)

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