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iris/triglyceride
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IRIS II study: the IRIS II score--assessment of a new clinical algorithm for the classification of insulin resistance in patients with Type 2 diabetes.
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OBJECTIVE
With the increasing availability of new drugs for the treatment of insulin resistance in patients with Type 2 diabetes, simple methods for their identification is an important challenge. The aim of our study was to compute a new algorithm for estimating insulin resistance in a routine
The effect of obesity on plasma triglycerides and fasting plasma IRI levels. Significance of insulinogenic index and glucose tolerance.
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6'-O-acetyl mangiferin from Iris rossii Baker inhibits lipid accumulation partly via AMPK activation in adipogenesis.
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Effective control of white adipose tissue accumulation would provide a therapeutic strategy for obesity, which poses a growing global problem. The plant chemical mangiferin stimulates adenosine monophosphate-activated protein kinase (AMPK), which inhibits adipogenesis and has therefore been
Effects of ethanolic extract of Iris germanica on lipid profile of rats fed on a high-fat diet.
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Ethanolic extract of Iris germanica rhizomes was investigated for hypolipidemic activity. I. germanica belong to the family Irdaceae and has been used to treat liver and spleen ailments in traditional system of medicine. Two groups of Wistar rats were fed with high-fat diet and ethanolic extract of
The IRIS V study: pioglitazone improves systemic chronic inflammation in patients with type 2 diabetes under daily routine conditions.
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BACKGROUND
The peroxisome proliferator-activated receptor-gamma agonist pioglitazone is established as a drug to treat patients with type 2 diabetes mellitus. In addition to lowering blood glucose levels, one of the favorable effects of pioglitazone is improvement of systemic chronic inflammation
Studies in congenital generalized lipodystrophy. IV. Effect of muscular exercise on carbohydrate and fat metabolism including plasma levels of IRI and HGH.
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Two patients with congenital generalized lipodystrophy have been studied at rest, and during and after long-term exercise at different carefully measured work loads. The two patients represented different stages of diabetes development. Both patients derived most of their energy used during muscular
[Relations between carbohydrate loading and arteriosclerosis. I. Behavior of triglycerides and NEFA in relation to the blood sugar and IRI levels in normal subjects and in patients with cardiovascular diseases after intravenous administration of glucose].
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[Glucocorticoid-induced hypertiglyceridemia: effects of cortisone acetate on triglyceride secretion rates and post-heparin lipolytic activity in rabbits (author's transl)].
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In order to elucidate the mechanisms of glucocorticoid-induced hypertriglyceridemia, 3mg or 10mg/kg of cortisone acetate were administered daily intramuscularly for 8 days to male albino rabbits which were fed 150g/day of a complete commercial diet. Plasma triglyceride (TG), cholesterol (Chol), free
Hyperinsulinemia and in vivo very-low-density lipoprotein-triglyceride kinetics.
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The effect of hyperinsulinemia (2 wk of twice daily NPH insulin) on the kinetics of very-low-density lipoprotein (VLDL)-triglyceride (TG) was studied in rats. To avoid profound hypoglycemia the rats were allowed sucrose ad libitum. Two control groups were needed: chow only and ad libitum
Prediction of infant birth weight by GDM screening tests. Importance of plasma triglyceride.
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OBJECTIVE
We measured plasma glucose, GHb, GPro, IRI and TG at 24-28-wk gestation to determine the extent of elevations in GDM and relationships to glucose intolerance and infant macrosomia.
METHODS
Plasma samples were obtained 1 h after ingestion of 50 g glucose after an overnight fast in 521
[Relationship of the value of excess body weight to the blood concentration of cholesterol and triglycerides and the level of the basic hormones regulating lipid metabolism in healthy men 30 to 50 years old].
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The basal levels of cholesterol (CS), triglycerides (TG), sugar, immunoreactive insulin (IRI), cortisol, testosterone, triiodothyronine (T3) and thyroxine (T4) were compared in 116 healthy males with risk factors of developing coronary heart disease (CHD), aged 45, engaged in administrative
The direct relationship of proinsulin-insulin hypersecretion to basal serum levels of cholesterol and triglyceride in myotonic dystrophy.
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Excessive pancreatic insulin secretory responses to a variety of beta-cytotropic agents have been observed in 40 to 60 per cent of subjects with myotonic dystrophy; in addition, 25 to 30 per cent of affected persons manifest mild glucose intolerance, suggesting that circulating insulin may be
Effects of ingestion of triglyceride or galactose on secretion of gastric inhibitory polypeptide and on responses to intravenous glucose in normal and diabetic subjects.
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Responses of plasma immunoreactive gastric inhibitory polypeptide (IRGIP) to oral triglyceride or galactose were compared in normal and mildly diabetic (non-insulin-dependent) subjects. After triglyceride the responses of IRGIP were similar, but after galactose those of the diabetics were slightly
Effects of synthetic androgen fluoxymesterone on triglyceride secretion rates in the rat.
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Fluoxymesterone, a C-17 methylated derivative of testosterone employed in the treatment of renal-failure patients with refractory anemia, was administered to Sprague-Dawley rats and the effects on plasma triglyceride (TG) and immunoreactive insulin (IRI) levels and the rate of hepatic triglyceride
The effects of prolonged fasting on plasma triglyceride kinetics in man.
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Studies were undertaken to examine triglyceride turnover in obese humans on isocaloric balanced diets and during prolonged (3-5 wk) fasting. The data were related to plasma concentrations of insulin (IRI), glucagon (IRG), and free fatty acids (FFA) and to blood ketone concentrations. The
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