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purpura fulminans/nécrose
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[Necrosis of maxilla secondary to purpura fulminans. A case report].
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Purpura fulminans in infants is a rare, life-threatening condition mostly due to Neisseria meningitides. The condition is often fatal unless there is early recognition of the clinical symptoms, prompt diagnosis, and judicious replacement therapy. We observed a case of maxilla necrosis in a
Penile necrosis secondary to purpura fulminans: a case report and review of literature.
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We report the case of a 60-year-old Hispanic male with widespread necrotic purpuric lesions involving the penile, suprapubic, inguinal and hip dermis due to purpura fulminans. Purpura fulminans describes a rare syndrome involving intravascular thrombosis and hemorrhagic infarction of the skin; this
Penile Necrosis as a Presenting Sign of Purpura Fulminans Mimicking Fournier's Gangrene
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We report the case of a 63-year-old white man who, 3 days after stent removal of endoscopic drainage of pancreatic cysts, developed a penile necrosis due to purpura fulminans (PF) that has been misdiagnosed as Fournier's gangrene. Penile necrosis was rapidly followed by a lethal multiorgan failure
Coumarin necrosis, neonatal purpura fulminans, and protein C deficiency.
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Protein C (PC), a 62,000-molecular weight vitamin K-dependent serine protease zymogen, is a natural anticoagulant that occurs in plasma at 4 mg/L. Activated PC inactivates clotting factors V and VIII and is also profibrinolytic. Activated PC is enhanced in its anticoagulant activity by protein S
The role of heparin in the prevention of extremity and digit necrosis in meningococcal purpura fulminans.
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In order to gather data regarding the utility of heparin therapy in limiting digit and extremity necrosis resulting from meningococcal purpura fulminans in children, we reviewed the charts of 24 pediatric patients with PF associated with meningococcal disease. Our study population was comprised of
Skin Necrosis and Purpura Fulminans in Children With and Without Thrombophilia--A Tertiary Center's Experience.
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Purpura fulminans (PF) is a very rare clinicopathologic skin disorder comprising dermal microvascular thrombosis associated with perivascular hemorrhage of multiple origins. It may occur as the presenting symptom of severe congenital deficiency of protein C (PC) or protein S (PS) during the newborn
Dermatopathology of skin necrosis associated with purpura fulminans.
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Dermal vascular skin necrosis is associated with a complex group of clinical disorders. Many of these disorders are associated with an underlying abnormality of the PC anticoagulant system or DIC, or both. The clinical appearance and histopathologic features of dermal vascular skin necrosis are
Acute Purpura Fulminans - a rare cause of skin necrosis: A single institution clinicopathological experience.
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Surgical treatment of extensive skin necrosis secondary to purpura fulminans in a patient with meningococcal sepsis.
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Meningococcal sepsis is associated with a high mortality rate. These patients may show severe disseminated intravascular coagulation (DIC) and skin necrosis. There is very little published experience regarding the surgical treatment of this complication. The similarity between skin necrosis
[Surgical management of cutaneous necrosis in the purpura fulminans: report of 2 clinical cases].
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The authors report their experience of the management of 2 patients with purpura fulminans. After a review of the epidemiology, diagnostic methods, natural course and prognosis of the disease, the various stages of the treatment are described. The urgency of the medical treatment is stressed and the
Proposed classification and pathologic mechanisms of purpura fulminans and skin necrosis.
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The syndromes of purpuric lesions associated with a thrombotic mechanism are very rare in the general population. Dermal vascular thrombosis, however, can be devastating and associated with significant morbidity and mortality. These syndromes share common features in their clinical course,
[Prevention of distal necrosis in purpura fulminans. Value of sodium nitroprusside and urokinase].
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Adult purpura fulminans and digital necrosis associated with sepsis and the factor V mutation.
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[Presence of necrosis of soft tissue in Henoch's purpura fulminans].
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[Purpura fulminans with large blemishes developing into deep tissue necrosis].
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