Hyperuricemia on Hypertension and Metabolic Syndrome
Keywords
Coimriú
Cur síos
Elevated consumption of high fructose corn syrup has lead to an increase of 30% of fructose intake since the last 20 years. Important data supporting this fact can be reflected on incidence and prevalence of Metabolic syndrome and hyperuricemia.
A peculiar effect of fructose intake demonstrated in animal models is the development of elevated uric acid levels; also some studies have found a clear association between hyperuricemia as an important risk factor for hypertension, diabetes mellitus, chronic kidney disease and metabolic syndrome.
Taking into account the existing evidence, our clinical research team presents this protocol as a way to evaluate the effect of uric acid treatment and its relation with Fructose consumption, metabolic syndrome parameters, hyperuricemia and risk of hypertension.
Confirming evidence with clinical basis may be the initial strategy to create primary prevention programs to control this health problems affecting Mexican Population.
Dátaí
| Fíoraithe Deireanach: | 06/30/2014 |
| Cuireadh isteach den chéad uair: | 07/06/2010 |
| Clárú Measta Curtha isteach: | 07/06/2010 |
| Arna chur suas ar dtús: | 07/07/2010 |
| Nuashonrú Deireanach Curtha isteach: | 07/22/2014 |
| Nuashonrú Deireanach Postáilte: | 07/23/2014 |
| Dáta Tosaigh an Staidéir Iarbhír: | 06/30/2010 |
| Dáta Críochnaithe Bunscoile Measta: | 01/31/2011 |
| Dáta Críochnaithe an Staid Mheasta: | 07/31/2011 |
Coinníoll nó galar
Idirghabháil / cóireáil
Drug: Allopurinol treatment
Other: Placebo
Céim
Grúpaí Láimhe
| Lámh | Idirghabháil / cóireáil |
|---|---|
| Active Comparator: Allopurinol treatment | Drug: Allopurinol treatment daily dosage |
| Placebo Comparator: Placebo | Other: Placebo daily dosage |
Critéir Incháilitheachta
| Aois Incháilithe le haghaidh Staidéir | 25 Years Chun 25 Years |
| Gnéas Incháilithe le haghaidh Staidéir | All |
| Glacann Oibrithe Deonacha Sláintiúla | Sea |
| Critéir | Inclusion Criteria: - adults with blood pressure from 120/80 mmHg and less than 140/90 mmHg - no pharmacological treatment for blood pressure control Exclusion Criteria: - hypertension (more than 140/90mmHg) - Diabetes Mellitus type 1 or 2 - Chronic kidney disease (MDRD less than 60) - Hepatic Disease - Malignancy - Pregnancy - patient receiving any medication |
Toradh
Bearta Toraidh Príomhúla
1. Effect of hyperuricemia treatment on systemic blood pressure [14 weeks]
Bearta Torthaí Tánaisteacha
1. Effect of hyperuricemia treatment on metabolic syndrome parameters [14 weeks]
