Effectiveness of Two Water-Based Potassium Oxalate Desensitizers

Ní féidir ach le húsáideoirí cláraithe ailt a aistriú

Logáil Isteach / Cláraigh

Sábháiltear an nasc chuig an gearrthaisce

StádasCríochnaithe

Urraitheoirí

Procter and Gamble

TRIAIL CHLINICIÚIL: NCT02192307

BioSeek: nct02192307

Keywords

Coimriú

This study will compare the safety and effectiveness of two water-based potassium oxalate desensitizers on existing dentinal hypersensitivity.

Dátaí

Fíoraithe Deireanach:	09/30/2019
Cuireadh isteach den chéad uair:	07/13/2014
Clárú Measta Curtha isteach:	07/13/2014
Arna chur suas ar dtús:	07/15/2014
Nuashonrú Deireanach Curtha isteach:	10/16/2019
Nuashonrú Deireanach Postáilte:	11/04/2019
Dáta na gcéad torthaí a cuireadh isteach:	08/29/2019
Dáta na dtorthaí QC a cuireadh isteach den chéad uair:	10/16/2019
Dáta na gcéad torthaí a cuireadh sa phost:	11/04/2019
Dáta Tosaigh an Staidéir Iarbhír:	06/30/2014
Dáta Críochnaithe Bunscoile Measta:	08/31/2014
Dáta Críochnaithe an Staid Mheasta:	08/31/2014

Coinníoll nó galar

Dentin Sensitivity

Idirghabháil / cóireáil

Device: Potassium oxalate

Céim

Grúpaí Láimhe

Lámh	Idirghabháil / cóireáil
Experimental: potassium oxalate gel Professional application
Active Comparator: Potassium oxalate liquid Professional application

Critéir Incháilitheachta

Aois Incháilithe le haghaidh Staidéir	18 Years Chun 18 Years
Gnéas Incháilithe le haghaidh Staidéir	All
Glacann Oibrithe Deonacha Sláintiúla	Sea
Critéir	Inclusion Criteria: - Provide written informed consent to participate in the study - Be at least 18 years of age - Be in good general health, as determined by the Investigator/designee based on review of the health history/update for participation in the study - Agree to refrain from participating in any other oral/dental product studies for the duration of the study - Agree to refrain from receiving any elective dentistry (including dental prophylaxis) for the duration of the study - Agree to refrain from using any oral hygiene products other than the assigned study products for the duration of the study - Agree to comply with study/product usage instructions; and - Have at least one tooth with gingival recession and hypersensitivity evidenced by a score of ≥ 1 on the Cold Air Sensitivity Schiff scale during screening Exclusion Criteria: - Gross oral neglect or urgent dental treatment needs - Severe periodontal disease and/or generalized mobility - Active treatment for periodontitis - Any disease or condition that could be expected to interfere with examination procedures or safe completion of the study - Self-reported pregnancy or nursing

Toradh

Bearta Toraidh Príomhúla

1. Change From Baseline Air Challenge [30 days]

The Schiff Sensitivity Scale was assessed for each test tooth via an evaporative air challenge. The examiner recorded the Schiff Index score corresponding to the response to the air challenge. The Schiff Index Sensitivity scale is scored as follows- 0: tooth/subject did not respond to stimulus, 1: tooth/subject responds to stimulus, but does not request discontinuation of stimulus, 2: tooth/subject responds to stimulus and requests discontinuation or moves form stimulus, 3: tooth/subject responds to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus. The higher the Schiff score, the more sensitive the tooth. The mean change from Baseline was calculated for this measure.

Bearta Torthaí Tánaisteacha

1. Change From Baseline Visual Analog Scale [30 Days]

Visual Analog Scale (VAS) - subjects are asked to look at a VAS and designate the level of hypersensitivity they experienced as a result of the thermal and water challenges using a continuum scale of 0 = No tooth pain up to 100 = Worst tooth pain ever experienced.

Effectiveness of Two Water-Based Potassium Oxalate Desensitizers

Keywords

oxalate

potaisiam

potassium oxalate

hypersensitivity