[Chemical Constituents from Saururus chinensis].
Keywords
Coimriú
OBJECTIVE
To investigate the chemical constituents of active components of Saururus chinensis on anti-nicotine withdrawal symptoms.
METHODS
Various column chromatography were used in the isolation and purification, and physiochemical constant determination and spectral analysis were adopted to determine the chemical structures.
RESULTS
Six chemical compounds were isolated from the active part of anti-withdrawal symptoms, and were identified as 4'-hydroxyl-3,3',4,5,5'-pentamethoxy-7,7'-epoxylignan (1) ,3-(2-nitroethyl)-1-methoxyindole(2), elemicin (3), erythro-(7R, 8S) - (-) - (3,4,5-trimethoxy-7-hydroxy-1'-allyl-3', 5'-dimethoxy)-8-O-4'-neolignan (4), 3,4,5-trimethoxy-phenylacrylaldehyde (5) and dibutyl phthalate (6).
CONCLUSIONS
Compound 1 is a novel lignan, compounds 2 - 6 are firstly isolated from this plant.
