atractyloside/athlasadh

Sábháiltear an nasc chuig an gearrthaisce

AiltTrialacha cliniciúlaPaitinní

Roghnaigh cineál sórtála

9 torthaí

Effects of the nonsteroidal anti-inflammatory drug piroxicam on energy metabolism in the perfused rat liver.

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Logáil Isteach / Cláraigh

1. The actions of piroxicam, a nonsteroidal and noncarboxylic anti-inflammatory drug, on the metabolism of the isolated perfused rat liver were investigated. The main purpose was to verify if piroxicam is also active on glycogenolysis and energy metabolism, as demonstrated for several carboxylic

Intra-cardiac remote ischemic post-conditioning attenuates ischemia-reperfusion injury in rats.

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Logáil Isteach / Cláraigh

OBJECTIVE It remains unknown whether brief occlusion and relaxation of remote non-infarct-related coronary arteries limits infarct size. We tested the hypothesis that repetitive, brief, non-infarcting ischemia in one remote myocardial region, applied before sustained reperfusion to another

Comparison of the toxicities, activities and chemical profiles of raw and processed Xanthii Fructus.

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Logáil Isteach / Cláraigh

BACKGROUND Although toxic, the Chinese medicinal herb Xanthii Fructus (XF) is commonly used to treat traditional Chinese medicine (TCM) symptoms that resemble cold, sinusitis and arthritis. According to TCM theory, stir-baking (a processing method) can reduce the toxicity and enhance the efficacy of

ATP-dependent potassium channels and mitochondrial permeability transition pores play roles in the cardioprotection of theaflavin in young rat.

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Logáil Isteach / Cláraigh

Previous studies have confirmed that tea polyphenols possess a broad spectrum of biological functions such as anti-oxidative, anti-bacterial, anti-tumor, anti-inflammatory, anti-viral and cardiovascular protection activities, as well as anti-cerebral ischemia-reperfusion injury properties. But the

Inhibition of glycogen synthase kinase 3 beta ameliorates liver ischemia reperfusion injury by way of an interleukin-10-mediated immune regulatory mechanism.

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Logáil Isteach / Cláraigh

The ubiquitous serine/threonine kinase glycogen synthase kinase 3 beta (Gsk3β) differentially regulates macrophage Toll-like receptor (TLR)-triggered pro- and anti-inflammatory cytokine programs. This study was designed to determine the in vivo role and therapeutic potential of Gsk3β modulation in

Galectin-3 but not galectin-1 induces mast cell death by oxidative stress and mitochondrial permeability transition.

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Logáil Isteach / Cláraigh

Galectin-1 and galectin-3 are the most ubiquitously expressed members of the galectin family and more importantly, these two molecules are shown to have opposite effects on pro-inflammatory responses and/or apoptosis depending on the cell type. Herein, we demonstrate for the first time that

Transgenic over expression of ectonucleotide triphosphate diphosphohydrolase-1 protects against murine myocardial ischemic injury.

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Logáil Isteach / Cláraigh

Modulation of purinergic signaling is critical to myocardial homeostasis. Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD-1; CD39) which converts the proinflammatory molecules ATP or ADP to AMP is a key regulator of purinergic modulation. However, the salutary effects of transgenic over

Protective effect of morin on myocardial ischemia‑reperfusion injury in rats.

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Logáil Isteach / Cláraigh

Morin, a natural flavonol, exhibits antioxidative, anti‑inflammatory and anti‑apoptotic effects in various pathological and physiological processes. However, whether morin exerts a protective effect on myocardial ischemia‑reperfusion injury (MIRI) is unknown. The present study aimed to determine the

Limb Ischemic Postconditioning Alleviates Postcardiac Arrest Syndrome through the Inhibition of Mitochondrial Permeability Transition Pore Opening in a Porcine Model.

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Logáil Isteach / Cláraigh

Previously, the opening of mitochondrial permeability transition pore (mPTP) was confirmed to play a key role in the pathophysiology of postcardiac arrest syndrome (PCAS). Recently, we demonstrated that limb ischemic postconditioning (LIpostC) alleviated cardiac and cerebral injuries

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Herbal & Natural Medicine

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