Bioassay-guided investigation of the bark of Elaeocarpus mastersii using KB (human oral epidermoid carcinoma) cells as a monitor led to the isolation of two cucurbitacins, cucurbitacin D and cucurbitacin F as cytotoxic principles, together with two ellagic acid derivatives, 4'-O-methylellagic acid
Elaeocarpus dolichostylus has afforded the new cucurbitacin derivative, hexanorcucurbitacin F (3), whose structure was determined by spectroscopic and chemical correlation with curcurbitacin F (1). Cucurbitacin F (1) and 23,24-dihydrocucurbitacin F (2) were also isolated in this study.