A nine year old Terrier-Chihuahua crossbred bitch was presented to the Western College of Veterinary Medicine with a history of anorexia, vomiting and diarrhea. A palpably enlarged uterus and purulent vaginal discharge were found on physical examination. Pyometra was diagnosed and ovariohysterectomy
The United States Immunodeficiency Network (USIDNET) patient registry was used to characterize the presentation, genetics, phenotypes, and treatment of patients with Hyper IgM Syndrome (HIGM).
The USIDNET Registry was queried for HIGM patient data collected from October 1992 to July 2015. Data