Intervention consists of daily administration of 2g probiotic Lactobacillus plantarum DR7, administered daily at a fixed dosage of 9 log CFU/sachet/day and continue for 12 weeks.
Intervention: Dietary Supplement: Lactobacillus plantarum DR7

Intervention consists of daily administration of 2g placebo (no probiotic bacteria), administered daily and continue for 12 weeks.
Intervention: Dietary Supplement: Placebo

Stress

This project aims to study the benefits of probiotics namely Lactobacillus plantarum DR7 for brain health benefits primarily to alleviate stress, among adults in Malaysia aged from 18-60 years. Secondary emphases include respiratory and gastrointestinal health

Lactobacillus plantarum DR7

Placebo

School of Industrial Technology, Universiti Sains Malaysia

Lactobacillus Plantarum DR7 for Gut-Brain-Axis Benefits

To evaluate the potential of oral administration of Lactobacillus plantarum DR7 in alleviation of stress using PSS questionnaire

To evaluate the potential of oral administration of Lactobacillus plantarum DR7 in alleviation of depression using DASS42 questionnaire

To evaluate the potential of oral administration of Lactobacillus plantarum DR7 in enhancing cognition ability using Cogstate Brief Battery

To evaluate the potential of oral administration of Lactobacillus plantarum DR7 in reducing upper respiratory episodes and symptoms using illness symptom chart

To evaluate the potential of oral administration of Lactobacillus plantarum DR7 in reducing diarrhea incidents using illness symptom chart

To evaluate the potential of oral administration of Lactobacillus plantarum DR7 in enhancing immunity via blood cytokines analyses

Min-Tze LIONG

Professor Dr.

Universiti Sains Malaysia

Clinical Nutrition Sdn Bhd

Placebo and DR7 will be administered via a parallel design

Masking will be subjected to Participant, Care Provider, Investigator

Hyperglycemia

Hypertension

volunteers will take only one capsule of stevioside (one day), and then corresponding measurements will be performed.

Purified extract of Rebaudina Stevia-Stevioside

Volunteers will take one capsule of saccharin 250mg (one day) and then, corresponding measurements will be performed

Sodium saccharin

Basque Public Health Service-Osakidetza (Lakuabizkarra primary care center and Txagorritxu hospital)

Effect of Stevioside in Postpandrial Glucose in Healthy Adults

Comparison of the Effect on Postpandrial Capillary Blood Glucose Between Oral Stevioside Versus Saccharin in Healthy Adults.

Change in capillary blood glucose levels after treatment

feeling of fullness, hunger and satiety after treatment

To describe and compare the adverse reactions of each treatment nausea, diarrhea, vomiting, allergic signs.

european/inmunostimulator

Lactobacillus Plantarum DR7 for Gut-Brain-Axis Benefits

Effect of Stevioside in Postpandrial Glucose in Healthy Adults

An bunachar luibheanna míochaine is iomláine le tacaíocht ón eolaíocht