swertia multicaulis/heipitíteas

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Leathanach 1 ó 25 torthaí

Seven new secoiridoids with anti-hepatitis B virus activity from Swertia angustifolia.

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Logáil Isteach / Cláraigh

Seven new secoiridoids, swertianglide (1) and swertianosides A-F (2-7), together with fifteen known compounds, were isolated from the whole plants of Swertia angustifolia. Their structures were elucidated on the basis of extensive spectroscopic analyses ([α](D), UV, IR, MS, 1D- and 2D-NMR). Fourteen

Swerilactones A and B, anti-HBV new lactones from a tradtional Chinese herb: Swertia mileensis as a treatment for viral hepatitis.

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Logáil Isteach / Cláraigh

Swerilactones A (1) and B (2), two novel lactones with an unprecedented 6/6/6/6/6 pentacyclic ring system, were isolated from the traditional Chinese herb of Swertia mileensis with activity against the hepatitis virus. Their structures and relative stereochemistry were elucidated based on

Two new secoiridoids and other anti-hepatitis B virus active constituents from Swertia patens.

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Logáil Isteach / Cláraigh

Two new secoiridoids, swerpatic acid (1) with an unusual C8 skeleton and swerpalactone (2), were isolated along with ten known compounds (3-12) from the whole plants of Swertia patens. Their structures were elucidated by comprehensive spectroscopic analyses. Eight compounds were evaluated for their

Three new secoiridoids, swermacrolactones A-C and anti-hepatitis B virus activity from Swertia macrosperma.

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Logáil Isteach / Cláraigh

Three new secoiridoids, swermacrolactones A-C (1-3), together with fourteen known compounds were isolated from Swertia macrosperma. Their structures were elucidated based on extensive spectroscopic analyses (IR, UV, MS, 1D and 2D NMR). By anti-HBV assay on the Hep G 2.2.15 cell line in vitro, the

Anti-hepatitis B virus active lactones from the traditional Chinese herb: Swertia mileensis.

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Logáil Isteach / Cláraigh

Swerilactones H-K (1-4), which are four novel lactones with an unprecedented C29 skeleton, were isolated from Swertia mileensis (Qing-Ye-Dan), an endemic Chinese herb used for treating viral hepatitis. Their structures were determined by extensive spectroscopic and X-ray crystallographic diffraction

Xanthones with anti-hepatitis B virus activity from Swertia mussotii.

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Logáil Isteach / Cláraigh

Two new xanthones, 8-O-β-D-glucopyranosyl-1-hydroxy-2,3,5-trimethoxyxanthone (1) and 8-O-[β-D-xylopyranosyl-(1 → 6)-β-D-glucopyranosyl]-1-hydroxy-2,3,5-trimethoxyxanthone (2), along with eighteen known xanthones (3-20) were isolated from Swertia mussotii. Their structures were elucidated on the

Anti-hepatitis B virus active constituents from Swertia chirayita.

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Logáil Isteach / Cláraigh

Four new compounds swertiachiralatone A (1), swertiachoside A (2), swertiachirdiol A (3) and swertiachoside B (4), together with twenty-six known ones were isolated from the ethanol extract of Swertia chirayita. Their structures were elucidated by extensive spectroscopic analyses (1D- and 2D-NMR,

Chemical constituents of Swertia delavayi and their anti-hepatitis B virus activity.

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Logáil Isteach / Cláraigh

Fifteen known compounds were isolated from Swertia delavayi by silica gel, Sephadex LH-20 and Rp-18 column chromatographies. Based on extensive spectroscopic analysis (MS, 1H, 13C-NMR), their structures were identified aserythrocentaurin (1), erythrocentaurindimethylacetal (2), sweroside (3),

Chemical constituents of Swertia mussotii and their anti-hepatitis B virus activity.

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Logáil Isteach / Cláraigh

Three new secoiridoid aglycones of (-)-swermusic acid A (1) and B (3), and (-)-swerimuslatone A (2), and four new secoiridoid glycosides of 6'-O-formylsweroside (4), 6'-O-formylgentiopicroside (5), 6'-O-acetylamarogentin (6) and 6'-O-acetylamaronitidin (7), along with 40 known compounds (8-47) were

Chemical constituents of Swertia yunnanensis and their anti-hepatitis B virus activity.

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Logáil Isteach / Cláraigh

Four new triterpenoids, sweriyunnangenin A (1), sweriyunnanosides A (2), B (3) and C (4), along with nineteen known compounds (5-23) were isolated from Swertia yunnanensis. Based on extensive spectroscopic analyses (1D- and 2D-NMR, HRESIMS, UV, IR, [α]D), the structures of sweriyunnangenin A (1),

Cloning and functional analysis of geraniol 10-hydroxylase, a cytochrome P450 from Swertia mussotii Franch.

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Logáil Isteach / Cláraigh

Swertia mussotii Franch has anti-hepatitis activity and contains a high level of iridoid monoterpenoids. The cytochrome P450 monooxygenase (CYP) geraniol 10-hydroxylase (G10H) is thought to play an important role in iridoid monoterpenoid and indole alkaloid biosynthesis. Here we report the isolation

Gentiocrucines A-E, five unusual lactonic enamino Ketones from Swertia macrosperma and Swertia angustifolia.

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Logáil Isteach / Cláraigh

Five unusual lactonic enamino ketones, gentiocrucines A-E (1-5), were isolated from Swertia macrosperma and S. angustifolia. Their structures were determined based on extensive spectroscopic analyses (IR, UV, MS, 1D- and 2D-NMR). By anti-HBV assay on the HepG 2.2.15 cell line in vitro, compound 1

Analyzing the hepatoprotective effect of the Swertia cincta Burkillextract against ANIT-induced cholestasis in rats by modulating the expression of transporters and metabolic enzymes.

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Logáil Isteach / Cláraigh

BACKGROUND Swertia cincta Burkill was traditionally used for treating jaundice and various types of chronic and acute hepatitis in Yunnan and Tibet in China for hundreds of years. This study aims to investigate the protective effect of S. cincta Burkill (ESC) extract on alpha-naphthylisothiocyanate

Identification of xanthones from Swertia punicea using high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

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Logáil Isteach / Cláraigh

BACKGROUND Swertia punicea Hemsl. (Gentianaceae) are used mainly for the treatment of acute bilious hepatitis, cholecystitis, fever, intoxification and jaundice in China, as a traditional Chinese folk medicine. Xanthones as the main chemical components of Swertia punicea have many possible

Swerilactones L-O, secoiridoids with C₁₂ and C₁₃ skeletons from Swertia mileensis.

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Logáil Isteach / Cláraigh

Swerilactones L-O (1-4), four unusual secoiridoids with unprecedented C₁₂ and C₁₃ skeletons, were isolated from the traditional Chinese herb Swertia mileensis. Compounds 1 and 2 had moderate inhibitory activities against the secretion of hepatitis B virus surface antigen (IC₅₀ = 1.47 and 1.20 mM,

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