Efficacy of a Naturally-derived Mouthrinse for Gingival Inflammation
कीवर्ड
सार
खजूर
अंतिम सत्यापित: | 06/30/2012 |
पहले प्रस्तुत किया गया: | 04/19/2009 |
अनुमानित नामांकन प्रस्तुत किया गया: | 04/20/2009 |
पहले पोस्ट किया गया: | 04/21/2009 |
अंतिम अद्यतन प्रस्तुत किया: | 07/15/2012 |
अंतिम अद्यतन पोस्ट: | 07/16/2012 |
वास्तविक अध्ययन प्रारंभ दिनांक: | 05/31/2009 |
अनुमानित प्राथमिक समापन तिथि: | 05/31/2010 |
अनुमानित अध्ययन पूर्णता तिथि: | 05/31/2010 |
स्थिति या रोग
हस्तक्षेप / उपचार
Drug: PERIORINSE
Drug: CPC
Drug: Listerine
Drug: placebo
चरण
शाखा समूह
बांह | हस्तक्षेप / उपचार |
---|---|
Experimental: PERIORINSE naturopathic remedy | Drug: PERIORINSE mouthwash;rinse full strength for 30 seconds with 20 ml (2/3 fl. Ounce or 4 teaspoonfuls) morning and night. |
Active Comparator: CPC Cepacol, standard anti-bacterial mouthwash | Drug: CPC mouthwash;rinse full strength for 30 seconds with 20 ml (2/3 fl. Ounce or 4 teaspoonfuls) morning and night. |
Active Comparator: Listerine standard anti-bacterial mouthwash | Drug: Listerine mouthwash;rinse full strength for 30 seconds with 20 ml (2/3 fl. Ounce or 4 teaspoonfuls) morning and night. |
Placebo Comparator: placebo colored water | Drug: placebo colored water mouthwash;rinse full strength for 30 seconds with 20 ml (2/3 fl. Ounce or 4 teaspoonfuls) morning and night. |
पात्रता मापदंड
युग अध्ययन के लिए पात्र | 14 Years सेवा 14 Years |
सेक्स अध्ययन के लिए पात्र | All |
स्वस्थ स्वयंसेवकों को स्वीकार करता है | हाँ |
मानदंड | Inclusion Criteria: - Age 14-75. - Clinical diagnosis of Gingivitis as measured by the Gingival index ≤ 0.5 - Healthy volunteer willing to cease all oral hygiene methods except for the mouthrinse for a period of three weeks. - Have at least 24 teeth in their mouth Exclusion Criteria: - Pregnant or planning to become pregnant during the study period. - Periodontal pockets greater than 5mm in 3 or more areas. - History of periodontal treatment within the last month. - Antibiotic treatment within the last month - Use of any antimicrobial mouthrinse within the last month. - Participation in another trial within one month prior to the study. - Inability to comply with the trial protocol by not rinsing with mouthrinse 20% of time. - Inability to comply, brushing the teeth or using another mouthrinse during the study period. - Systemic Disease. - On antibiotic or anti-inflammatory medication - Cigarette-smoking |
परिणाम
प्राथमिक परिणाम उपाय
1. Difference in the Gingival Index scores between the start and the end of the study [14 days]
माध्यमिक परिणाम उपाय
1. The difference in C-Reactive protein levels between the start and the end of the study. [14 days]