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Experimental Research on Deep Carious Lesion Treatment of Molars

केवल पंजीकृत उपयोगकर्ता ही लेखों का अनुवाद कर सकते हैं
साइन अप करने के लिए लॉग इन करें
लिंक क्लिपबोर्ड पर सहेजा गया है
स्थितिसक्रिय, भर्ती नहीं
प्रायोजक
Carol Davila University of Medicine and Pharmacy

कीवर्ड

सार

Maintaining dental pulp vitality is crucial for tooth preservation and functionality. Untreated dental caries may lead to pulp necrosis and infection, affecting children's growth and well-being. The first permanent teeth erupt around 6 years old. These are the first molars (FPM), which are frequently affected by caries, soon after their eruption.
In the present application, our main goal is to determine whether two treatment groups (MTA and TheraCal) are long-term effective in preserving pulp vitality among children' FPM affected by deep caries.

विवरण

Among the most frequently used materials for pulp capping are calcium hydroxide, mineral trioxide aggregate (MTA), and, more recent, TheraCal. All of them are biocompatible and induce the formation of coronal hard tissue barriers (tertiary reparative dentin). Calcium hydroxide, considered for a long time the gold standard of direct pulp capping materials, has excellent antibacterial and remineralisant properties; however, it lacks adhesion, especially at moist dentin, and reparative dentin is less homogenous.

MTA proved to stimulate protective dentin bridge formation without inflammatory changes and least necrosis. It is also moisture tolerant, but it is more expensive, has poor handling characteristics and slow setting time.

TheraCal bonds to deep moist dentin, has strong physical properties, no solubility, high radioopacity and higher calcium releasing abilities than MTA or calcium hydroxide.

खजूर

अंतिम सत्यापित: 12/31/2019
पहले प्रस्तुत किया गया: 07/31/2018
अनुमानित नामांकन प्रस्तुत किया गया: 08/08/2018
पहले पोस्ट किया गया: 08/12/2018
अंतिम अद्यतन प्रस्तुत किया: 01/25/2020
अंतिम अद्यतन पोस्ट: 01/27/2020
वास्तविक अध्ययन प्रारंभ दिनांक: 01/07/2018
अनुमानित प्राथमिक समापन तिथि: 09/30/2020
अनुमानित अध्ययन पूर्णता तिथि: 03/31/2021

स्थिति या रोग

Dental Caries in Children

हस्तक्षेप / उपचार

Other: TheraCal

Other: Mineral trioxide aggregate (MTA)

चरण

-

शाखा समूह

बांहहस्तक्षेप / उपचार
Experimental: TheraCal
Indirect pulp capping with TheraCal
Other: TheraCal
Caries removal without pulp exposure (stepwise excavation) followed by indirect pulp capping with TheraCal
Active Comparator: Mineral trioxide aggregate (MTA)
Indirect pulp capping with MTA
Other: Mineral trioxide aggregate (MTA)
Caries removal without pulp exposure (stepwise excavation) followed by indirect pulp capping with MTA

पात्रता मापदंड

युग अध्ययन के लिए पात्र 6 Years सेवा 6 Years
सेक्स अध्ययन के लिए पात्रAll
स्वस्थ स्वयंसेवकों को स्वीकार करता हैहाँ
मानदंड

Inclusion Criteria:

- untreated deep uncomplicated carious lesions in first permanent molars (FPM)

- absence of clinical diagnosis of pulp exposure

- fistula

- swelling of periodontal tissues

- abnormal tooth mobility

- history of spontaneous pain or sensitivity to percussion

- healthy appearance of adjacent gingiva

- normal tooth color

- positive vitality to thermal and electric tests.

Exclusion Criteria:

- FPM with previous treatment

- FPM with developmental abnormalities (such as enamel hypoplasia, dentinogenesis imperfecta etc.)

- children with mental disabilities or systemic diseases.

परिणाम

प्राथमिक परिणाम उपाय

1. Clinical pulpal survival rate [20 months]

Pulpal survival is defined by positive response without lingering sensation to the cold test, absence of clinical signs and symptoms, and no apical radiolucency on the periapical radiograph.

माध्यमिक परिणाम उपाय

1. Incidence of apical root maturation (apexogenesis) [20 months]

We will investigate the treatment effect on apexogenesis in children who had incomplete root formation at the beginning of the study and preserve their pulp vitality at the end of the study. The outcome will be compared radiographically with apical maturation in molar pairs (healthy contralateral molar, where applicable).

हमारे फेसबुक पेज से जुड़ें

विज्ञान द्वारा समर्थित सबसे पूर्ण औषधीय जड़ी बूटी डेटाबेस

  • 55 भाषाओं में काम करता है
  • विज्ञान द्वारा समर्थित हर्बल इलाज
  • छवि द्वारा जड़ी बूटी की मान्यता
  • इंटरएक्टिव जीपीएस नक्शा - स्थान पर टैग जड़ी बूटियों (जल्द ही आ रहा है)
  • अपनी खोज से संबंधित वैज्ञानिक प्रकाशन पढ़ें
  • उनके प्रभाव से औषधीय जड़ी बूटियों की खोज करें
  • अपने हितों को व्यवस्थित करें और समाचार अनुसंधान, नैदानिक परीक्षणों और पेटेंट के साथ अद्यतित रहें

एक लक्षण या बीमारी टाइप करें और जड़ी-बूटियों के बारे में पढ़ें जो मदद कर सकती हैं, एक जड़ी बूटी टाइप करें और बीमारियों और लक्षणों को देखें जिनके खिलाफ इसका उपयोग किया जाता है।
* सभी जानकारी प्रकाशित वैज्ञानिक शोध पर आधारित है

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