Different Does of Acupuncture on Premenstrual Syndrome Efficacy Analysis
Ključne riječi
Sažetak
Opis
Premenstrual syndrome (PMS) is the sum of a group of symptoms (including physical and psychological symptoms) that occurs during the luteal phase of the menstrual cycle. Women who have such symptoms have been estimated as high as 75%; of which 3% to 8% are severe symptoms, called premenstrual dysphoric disorder (premenstrualdysphoric syndrome, PMDD). The two groups are very similar. PMS is mostly for physical discomfort, while PMDD is for emotional problems, affecting women's sleep seriously.
Regarding the treatment of premenstrual syndrome (PMS), western medicine adopt oral contraceptive pills (OCP) as the first-line medication. However, the common side effects of OCP, such as headache, dizziness, nausea, vomiting, depression, breast pain and so on are also troublesome, In recent years, some women also use acupuncture as an adjunctive replacement therapy because of its safety and fewer side effects. Nevertheless, the factors affecting treatment effect of acupuncture and moxibustion. such as the selection of acupoint s ( of which meridians) or number(dose) of acupuncture ,etc., maight affect the efficacy, yet the relevant research on this issue is not enough. In traditional Chinese medicine theory, acupuncture and moxibustion regulate the energy of the meridians and adjust blood and qi, which in turn help the balance of yin and yang. Female menstrual cycle is a process of conversion between yin and yang in TCM theory. While in western medicine, it is regulated by the endocrine system.
Datumi
| Posljednja provjera: | 01/31/2020 |
| Prvo podneseno: | 03/02/2020 |
| Predviđena prijava poslana: | 03/03/2020 |
| Prvo objavljeno: | 03/04/2020 |
| Posljednje ažuriranje poslano: | 03/03/2020 |
| Posljednje ažuriranje objavljeno: | 03/04/2020 |
| Stvarni datum početka studija: | 12/31/2018 |
| Procijenjeni datum primarnog završetka: | 09/17/2020 |
| Procijenjeni datum završetka studije: | 09/17/2020 |
Stanje ili bolest
Intervencija / liječenje
Drug: Conventional Gynecologic Treatment group
Device: Low dose acupuncture group
Device: High dose acupuncture group
Faza
Grupe ruku
| Ruka | Intervencija / liječenje |
|---|---|
| Active Comparator: Conventional Gynecologic Treatment group Taking NSAIDs or oral contraceptives.NSAIDs include Ibuprofen, Naproxen, Diclofenac, and Piroxicam. Oral contraceptives include Yasmin. | Drug: Conventional Gynecologic Treatment group Taking NSAIDs or oral contraceptives.NSAIDs include Ibuprofen, Naproxen, Diclofenac, and Piroxicam. Oral contraceptives include Yasmin. |
| Experimental: Low dose acupuncture group Acupuncture has fewer acupuncture points. | Device: Low dose acupuncture group Six acupoints: Three Yin Intersection( SP6)、Grandfather Grandson(SP4)、 Sea of Blood(SP10) 、Sea of Qi(RN6)、Origin Pass(RN4) 、Inner Pass(PC6) |
| Experimental: High dose acupuncture group Acupuncture has more acupuncture points. | Device: High dose acupuncture group Twelve acupoints: Three Yin Intersection( SP6)、Grandfather Grandson(SP4)、 Sea of Blood(SP10) 、Sea of Qi(RN6)、Origin Pass(RN4) 、Middle Extremity(RN3)、Inner |
Kriterij prihvatljivosti
| Dobni uvjeti za studiranje | 19 Years Do 19 Years |
| Spolovi koji ispunjavaju uvjete za studij | Female |
| Prihvaća zdrave volontere | Da |
| Kriteriji | Inclusion Criteria: 1.15 to 49 years 2.with a history of regular menstrual cycles (28days±7 days) 3.Symptoms：breast pain、dizziness、bloating、cramps、nausea、vomiting、 diarrhea、headache、 fatigue，etc Exclusion Criteria: 1. irregular menstrual cycles 2. intrauterine contraceptive device (IUCD/IUD) 3. uncontrolled neurological diseases 4. lactation， pregnant women，or those with plans to get pregnant in the coming half year |
Ishod
Primarne mjere ishoda
1. Wang Qi Chinese Medicine Questionnaire [Change from Baseline TCM constitutions at 4 cycles (each cycle is 30 days).]
Sekundarne mjere ishoda
1. Visual analogue scale(VAS) score [Change from Baseline VAS score at 4 cycles (each cycle is 30 days).]
2. Blood test estrogen [Change from Baseline blood test at 4 cycles (each cycle is 30 days).]
3. Blood test progesterone [Change from Baseline blood test at 4 cycles (each cycle is 30 days).]
4. Blood test prostaglandin [Change from Baseline blood test at 4 cycles (each cycle is 30 days).]
5. Menstrual Distress Questionnaire(MDQ) [Change from Baseline Menstrual Distress Questionnaire at 4 cycles (each cycle is 30 days).]
