Exercise Training in Patients With Non-cystic Fibrosis (CF) Bronchiectasis
Ključne riječi
Sažetak
Opis
Bronchiectasis not related to cystic fibrosis (non-CF bronchiectasis) is a chronic respiratory condition characterised by permanent dilatation of the airways arising from bronchial inflammation and infection. Predominant symptoms include daily productive cough, dyspnoea and generalised fatigue. This profile is associated with diminished health-related quality of life (HRQOL) and reduced exercise tolerance.
Available medical treatments for bronchiectasis include antibiotic and inhalation therapy. To date, there is no evidence that these treatments can reduce the exacerbation rate or modify the rate of disease progression. While international guidelines for pulmonary rehabilitation recommend the inclusion of patients with bronchiectasis, there is a deficiency in evidence supporting exercise training in this population. It is proposed that a standard exercise training program conducted according to Australian guidelines for pulmonary rehabilitation will improve both exercise capacity, quality of life and reduce the number of acute infections in both the short and long term in people with bronchiectasis.
Datumi
| Posljednja provjera: | 02/28/2014 |
| Prvo podneseno: | 04/20/2009 |
| Predviđena prijava poslana: | 04/20/2009 |
| Prvo objavljeno: | 04/21/2009 |
| Posljednje ažuriranje poslano: | 03/09/2014 |
| Posljednje ažuriranje objavljeno: | 03/10/2014 |
| Stvarni datum početka studija: | 01/31/2009 |
| Procijenjeni datum primarnog završetka: | 01/31/2013 |
| Procijenjeni datum završetka studije: | 01/31/2013 |
Stanje ili bolest
Intervencija / liječenje
Other: Exercise
Faza
Grupe ruku
| Ruka | Intervencija / liječenje |
|---|---|
| Experimental: Exercise 8 week, twice weekly exercise program with both endurance and upper and lower limb strength training | Other: Exercise 8 week, twice weekly exercise program with endurance and upper and lower limb strength training |
| No Intervention: 2 No exercise, twice weekly phone calls |
Kriterij prihvatljivosti
| Dobni uvjeti za studiranje | 20 Years Do 20 Years |
| Spolovi koji ispunjavaju uvjete za studij | All |
| Prihvaća zdrave volontere | Da |
| Kriteriji | Inclusion Criteria: - Diagnosis of bronchiectasis (HRCT) - Stable medical status for last 4 weeks - History of 2 exacerbations in the last 2 years - Dysnpoea on exertion (Modified Medical Research Council score >1) Exclusion Criteria: - Concurrent diagnosis of COPD (physician diagnosis and history of 10 pack year smoking) - Concurrent diagnosis of asthma (history of atopic disease and evidence of bronchodilator reversibility of 12% or 200ml in FEV1 or FVC) - Concurrent diagnosis of Interstitial lung disease - Concurrent diagnosis of Cystic Fibrosis - Medical condition which could place patient at risk during exercise training (angina, neurological or orthopaedic condition) - Prior completion of pulmonary rehabilitation within the last 12 months |
Ishod
Primarne mjere ishoda
1. Incremental Shuttle Walk Test Chronic Respiratory Disease questionnaire [July 2011]
Sekundarne mjere ishoda
1. 6-Minute Walk Test [July 2011]
