Green Tea in Breast Cancer Patients
Ključne riječi
Sažetak
Datumi
| Posljednja provjera: | 02/28/2018 |
| Prvo podneseno: | 07/28/2009 |
| Predviđena prijava poslana: | 07/29/2009 |
| Prvo objavljeno: | 07/30/2009 |
| Posljednje ažuriranje poslano: | 03/27/2018 |
| Posljednje ažuriranje objavljeno: | 03/29/2018 |
| Stvarni datum početka studija: | 05/06/2008 |
| Procijenjeni datum primarnog završetka: | 12/13/2010 |
| Procijenjeni datum završetka studije: | 06/05/2016 |
Stanje ili bolest
Intervencija / liječenje
Dietary Supplement: tea capsules
Faza
Grupe ruku
| Ruka | Intervencija / liječenje |
|---|---|
| Active Comparator: tea capsules 3 tea capsules daily for 3 weeks | Dietary Supplement: tea capsules 3 tea capsules daily for 3 weeks |
| No Intervention: Control No tea capsules |
Kriterij prihvatljivosti
| Dobni uvjeti za studiranje | 18 Years Do 18 Years |
| Spolovi koji ispunjavaju uvjete za studij | Female |
| Prihvaća zdrave volontere | Da |
| Kriteriji | Inclusion Criteria: - Postmenopausal (at least 2 years since last menstrual period) or age 55 or older if prior hysterectomy - Non-current (not with past 6 months) user of menopausal hormones - Mammographic abnormality consistent with any type of incident breast cancer necessitating a diagnostic biopsy (BIRAD IV(b), (c) or V) will be sufficient to draw baseline LFT and complete screening questionnaire. Unless the biopsy confirms incident breast cancer, such subjects will not be included in further research interventions and they will not serve as EGCG treated or control subjects. - Diagnosed with incident breast cancer on the diagnostic biopsy is required for inclusion in the EGCG or control treatment groups. - Non-green tea drinker (less than monthly) - this criteria does not apply to black tea or herbal tea - Provided written informed consent Exclusion Criteria: - Green tea drinker (once per month or more) - History of breast cancer or other cancer including a prior diagnosis of any type of incident breast cancer. - Known allergy to tea - Abnormal liver enzymes (plus or minus 10% of the normal ranges). |
Ishod
Primarne mjere ishoda
1. level of reduction in proliferation or increase in apoptosis in association with short-term EGCG [At surgery]
