Epidermolysis bullosa simplex (EBS), is a disorder resulting from mutations in the genes encoding keratin 5 or keratin 14.Blister formation of EBS occurs at the dermoepidermal junction. Sometimes EBS is called epidermolytic.
Absence of keratin-5,14 since birth.
Epidermolysis bullosa simplex may be divided into multiple types:
Protect skin, stop blister formation, promote healing
Prevent complications
Necessary treatment: use oral and topical steroid for heal
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