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American Journal of Ophthalmology 2004-May

Panophthalmitis due to clostridium septicum.

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Daniel C Schickner
Alon Yarkoni
Paul Langer
Larry Frohman
Xue Chen
Robert Folberg
Lucian V Del Priore

Ključne riječi

Sažetak

OBJECTIVE

To describe patient survival in a rare case of endogenous Clostridium septicum sepsis with panophthalmitis.

METHODS

Observational case report.

METHODS

Both eyes of a female patient were examined in a hospital setting.

RESULTS

A 68-year-old woman had right orbital pain, proptosis, panophthalmitis, mental confusion and fever for 2 days. Blood cultures were significant for Clostridium septicum. The patient did not improve after treatment with intravenous broad-spectrum antibiotics and the right eye was enucleated. The patient survived the acute infection and extensive systemic evaluation revealed an undiagnosed colon carcinoma that may have been responsible for colonization and vascular dissemination of Clostridium septicum.

CONCLUSIONS

Clostridium septicum panophthalmitis and sepsis can be the presenting sign in patients with unsuspected malignancies, particularly colon cancer. Patients can survive the infection with aggressive therapy with systemic antibiotics combined with removal of the infected tissue.

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