6 rezultatima
FIELD OF THE INVENTION
The present invention relates to the field of medicine. More specifically, the invention relates to an andrographolide enteric targeting micropellet and a method for preparation thereof. Also, the present invention relates to a use of andrographolide and andrographolide
FIELD OF INVENTION
The present invention relates to novel andrographolide derivatives and use thereof in manufacture of medicaments.
BACKGROUND OF THE INVENTION
Andrographolide (Andro) is the main active component of the herb Andrographis (Chinese name: "Chuanxinlian" or Latin name: Herba
BACKGROUND
Tumor necrosis factor alpha (TNF.alpha.), a mononuclear cytokine, is predominately produced by monocytes and macrophages. It possesses various biological activities: (1) killing cancer cells or inhibiting growth of cancer cells, (2) enhancing the phagocytosis of neutrophilic granulocytes,
CROSS REFERENCE TO RELATED APPLICATION
This is a National Stage of International Application PCT/EP2007/006666, filed 27 Jul. 2007, which claims the benefit of Application No. 06016518.0, filed in Europe on 8 Aug. 2006, the disclosures of which Applications are incorporated by reference
BACKGROUND
Inflammatory bowel disease includes chronic gastrointestinal disorders characterized by infiltration of inflammatory cells into the mucosa of the digestive tract. Ulcerative colitis and Crohn's disease are two prevalent conditions among them.
Ulcerative colitis takes place in the large
BACKGROUND
Inflammatory bowel disease includes chronic gastrointestinal disorders characterized by infiltration of inflammatory cells into the mucosa of the digestive tract. Ulcerative colitis and Crohn's disease are two prevalent conditions among them.
Ulcerative colitis takes place in the large