Patients receive standard androgen deprivation therapy (ADT) with a gonadotropin-releasing hormone (GnRH) agonist (such as leuprolide, goserelin, buserelin, or triptorelin) for 24 months from initiation and oral (PO) antiandrogen (such as flutamide or bicalutamide) beginning 2 months prior and for the duration of radiation therapy (RT).

Patients receive the same standard ADT with a GnRH agonist and oral antiandrogen. In addition, patients also receive steroid 17alpha-monooxygenase TAK-700 (TAK-700) PO twice daily (BID) for 2 years.

Prostate Cancer

bicalutamide

buserelin

flutamide

goserelin acetate

leuprolide acetate

orteronel

triptorelin

The Kirklin Clinic at Acton Road

University of Alabama at Birmingham

Arizona Oncology-Deer Valley Center

Arizona Oncology Services Foundation

Sutter Cancer Centers Radiation Oncology Services-Auburn

Sutter Cancer Centers Radiation Oncology Services-Cameron Park

Mercy San Juan Medical Center

Veterans Administration Long Beach Medical Center

Los Angeles County-USC Medical Center

University of Southern California/Norris Cancer Center

Cedars-Sinai Medical Center

Pomona Valley Hospital Medical Center

Rohnert Park Cancer Center

Sutter Cancer Centers Radiation Oncology Services-Roseville

Sutter General Hospital

University of California At San Diego

UCSF-Mount Zion

Kaiser Permanente Medical Center - Santa Clara

Kaiser Permanente Cancer Treatment Center

Stanford University Hospitals and Clinics

Sutter Cancer Centers Radiation Oncology Services-Vacaville

Sutter Solano Medical Center

University of Colorado Cancer Center - Anschutz Cancer Pavilion

Poudre Valley Radiation Oncology

Hartford Hospital

The Hospital of Central Connecticut

William Backus Hospital

Helen F Graham Cancer Center

Christiana Care Health System-Christiana Hospital

University of Miami Sylvester Comprehensive Cancer Center at Deerfield Beach

University of Miami Miller School of Medicine-Sylvester Cancer Center

Florida Hospital

Grady Health System

Piedmont Hospital

Emory University/Winship Cancer Institute

Atlanta VA Medical Center

Saint Joseph's-Candler Health System

Queen's Medical Center

Saint Alphonsus Regional Medical Center

Idaho Urologic Institute PA

Weiss Memorial Hospital

Decatur Memorial Hospital

Hines Veterans Administration Hospital

Loyola University Medical Center

OSF Saint Francis Medical Center

Radiation Oncology Associates PC

Parkview Hospital Randallia

University of Iowa Hospitals and Clinics

University of Kansas Medical Center

Kansas City Cancer Centers-Southwest

University of Kentucky

Mary Bird Perkins Cancer Center

Touro Infirmary

Ochsner Medical Center Jefferson

Maine Medical Center- Scarborough Campus

Saint Agnes Hospital

Peninsula Regional Medical Center

Massachusetts General Hospital Cancer Center

Brigham and Women's Hospital

Dana-Farber Cancer Institute

Beth Israel Deaconess Medical Center

Saint Anne's Hospital

Dana-Farber/Brigham and Women's Cancer Center at Milford Regional

North Shore Medical Center Cancer Center

Dana-Farber/Brigham and Women's Cancer Center at South Shore

Bixby Medical Center

Saint Joseph Mercy Hospital

University of Michigan

McLaren-Flint

West Michigan Cancer Center

Great Lakes Cancer Institute-Lapeer Campus

McLaren Cancer Institute-Owosso

Northern Michigan Regional Hospital

William Beaumont Hospital-Royal Oak

William Beaumont Hospital - Troy

Sanford Clinic North-Bemidgi

Saint Luke's Hospital of Duluth

Regions Hospital

Southeast Cancer Center

Kansas City Cancer Center - South

Kansas City Cancer Centers - North

Kansas City Cancer Center-Lee's Summit

Washington University School of Medicine

Siteman Cancer Center-South County

Missouri Baptist Medical Center

Barnes-Jewish West County Hospital

Saint John's Mercy Medical Center

Siteman Cancer Center - Saint Peters

Mercy Hospital Springfield

Benefis Healthcare- Sletten Cancer Institute

Nebraska Methodist Hospital

The Nebraska Medical Center

Concord Hospital

Exeter Hospital

Dartmouth Hitchcock Medical Center

Elliot Hospital

Cooper Hospital University Medical Center

Saint Peter's University Hospital

MD Anderson Cancer Center at Cooper-Voorhees

Sanford Bismarck Medical Center

Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer

Phase III Trial of Dose Escalated Radiation Therapy and Standard Androgen Deprivation Therapy (ADT) With a GNRH Agonist vs. Dose Escalated Radiation Therapy and Enhanced ADT With a GNRH Agonist and TAK-700 For Men With High Risk Prostate Cancer

Radiation Therapy Oncology Group

National Cancer Institute (NCI)

NRG Oncology

Princess Margaret Hospital

An Alternative to A Fixed Schedule In Management Of Prostate Cancer

Testosterone-Guided Schedule of Androgen Deprivation Therapy (ADT) as an Alternative to A Fixed Schedule In Management Of Prostate Cancer

University Health Network, Toronto

antiandrogens

moždani udar

stroke

antiandrogens/moždani udar

Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer

An Alternative to A Fixed Schedule In Management Of Prostate Cancer

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