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armepavine/leukemija

Veza se sprema u međuspremnik
ČlanciKlinička ispitivanjaPatenti
2 rezultatima

Armepavine oxalate induces cell death on CCRF-CEM leukemia cell line through an apoptotic pathway.

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Prijava Registriraj se
Drug-induced cell death can occur as a result of DNA damage, which in turn may lead to the reduction of bcl-2 expression and activation of caspase-3 expression. In the present study, we investigated the effect of armepavines and atherosperminine on the cell survival rate and expression of bcl-2 and

Bisbenzylisoquinoline alkaloids and P-glycoprotein function: A structure activity relationship study

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Prijava Registriraj se
Conflicts with the notion that specific substrate interactions were required in the control of reaction path in active transport systems, P-glycoprotein showed extraordinarily low specificity. Therefore, overexpression P-glycoprotein excluded a large number of anticancer agents from cancer cells,
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