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Stranica 1 iz 177 rezultatima
Biomarkers and targets for diagnosis, prognosis and management of prostate, breast and bladder cancer
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BACKGROUND OF THE INVENTION
A. Field of the Invention
The present invention relates generally to nucleic acid sequences useful as probes for the diagnosis of cancer and methods relating thereto. More particularly, the present invention concerns probes and methods useful in diagnosing, identifying
Double-stranded nucleic acid molecule cancer cell proliferation inhibitor and pharmaceutical agent suitable for prevention or treatment of uterine cancer, breast cancer, and bladder cancer
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TECHNICAL FIELD
The present invention relates to a double-stranded nucleic acid molecule (e.g., siRNA) suitable for the prevention or treatment of uterine, breast and bladder cancers; a cancer cell proliferation inhibitor containing the double-stranded nucleic acid molecule; and a pharmaceutical
Methods for treating cancer using ephrin type-A receptor 10 antibodies conjugated to cytotoxic agents
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INTRODUCTION
The present invention relates to the identification of membrane protein associated with bladder cancer, breast cancer, colorectal cancer, head and neck cancer, kidney cancer, lung cancer and pancreatic cancer which has utility as a marker for bladder cancer, breast cancer, colorectal
Nitrogen-containing aromatic heterocyclic compound
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TECHNICAL FIELD
The present invention relates to compounds useful as active ingredients in pharmaceutical compositions, particularly in pharmaceutical compositions for the treatment of mutant FGFR3-positive bladder cancer.
BACKGROUND ART
The signaling pathway induced by fibroblast growth factors
Method for treating cancer by administering antibody to ephrin type-A receptor 7
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a U.S. National Phase of PCT Patent Application No. PCT/IB2009/005884 filed Jun. 9, 2009 and claims priority to Provisional Patent Application No. 61/060,067 filed Jun. 9, 2008 the disclosures of which are incorporated herein by reference
PRMT1 for target genes of cancer therapy and diagnosis
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TECHNICAL FIELD
1. Technical Field
The present invention relates to methods of detecting and diagnosing a predisposition to developing cancer, particularly bladder cancer, gastric cancer, colorectal cancer, breast cancer, esophageal cancer, lung cancer, lymphoma, pancreatic cancer and testicular
RNAi probes targeting cancer-related proteins
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This application claims the benefit and priority of U.S. Provisional Applications Nos. 60/405,193, filed Aug. 21, 2002, 60/408,152 filed Sep. 3, 2002, and 60/472,387, filed May 20, 2003, all of which are incorporated herein by reference.
BACKGROUND OF THE INVENTION
This application relates to short
RNAi probes targeting cancer-related proteins
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BACKGROUND OF THE INVENTION
This application relates to short double stranded RNAi probes useful in cancer therapy and treatment of other diseases. RNA interference or "RNAi" is a term initially coined by fire and co-workers to describe the observation that double-stranded RNA (dsRNA) can block gene
RNAi probes targeting cancer-related proteins
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BACKGROUND OF THE INVENTION
This application relates to short double stranded RNAi probes useful in cancer therapy and treatment of other diseases. RNA interference or "RNAi" is a term initially coined by Fire and co-workers to describe the observation that double-stranded RNA (dsRNA) can block gene
RNAi probes targeting cancer-related proteins
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BACKGROUND OF THE INVENTION
This application relates to short double stranded RNAi probes useful in cancer therapy and treatment of other diseases. RNA interference or "RNAi" is a term initially coined by Fire and co-workers to describe the observation that double-stranded RNA (dsRNA) can block gene
RNAi probes targeting cancer-related proteins
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BACKGROUND OF THE INVENTION
This application relates to short double stranded RNAi probes useful in cancer therapy and treatment of other diseases. RNA interference or "RNAi" is a term initially corned by Fire and co-workers to describe the observation that double-stranded RNA (dsRNA) can block gene
Antibody drug conjugates (ADC) that bind to 158P1D7 proteins
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SUBMISSION OF SEQUENCE LISTING ON ASCII TEXT FILE
The content of the following submission on ASCII text file is incorporated herein by reference in its entirety: a computer readable form (CRF) of the Sequence Listing (file name: 511582505002SeqList.txt, date recorded: Mar. 25, 2016, size: 40,227
Antibody drug conjugates (ADC) that bind to 158P1D7 proteins
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STATEMENT OF RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH
Not applicable.
SUBMISSION OF SEQUENCE LISTING ON ASCII TEXT FILE
The content of the following submission on ASCII text file is incorporated herein by reference in its entirety: a computer readable form (CRF) of the Sequence
Antibody drug conjugates (ADC) that bind to 158P1D7 proteins
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SUBMISSION OF SEQUENCE LISTING ON ASCII TEXT FILE
This application incorporates by reference the Computer Readable Form (CRF) of a Sequence Listing in ASCII text format submitted via EFS-Web. The Sequence Listing text file submitted via EFS-Web, entitled 14369-241-999_SEQ_LISTING.txt, was created on
Histone demethylase inhibitors
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BACKGROUND
A need exists in the art for an effective treatment of cancer and neoplastic disease.
BRIEF SUMMARY OF THE INVENTION
Provided herein are substituted pyrazolylpyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are
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