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butanedione/edema

Veza se sprema u međuspremnik
ČlanciKlinička ispitivanjaPatenti
3 rezultatima
BACKGROUND Reperfusion injury after cardioplegia may not be sufficiently addressed by conventional cardioplegic techniques in open heart surgery. 2,3-butanedione monoxime (BDM) has the potential to reduce myocardial reperfusion injury by uncoupling myocyte contraction from the intracellular calcium

University of Wisconsin solution with butanedione monoxime and calcium improves rat lung preservation.

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Prijava Registriraj se
BACKGROUND A limitation to fully using lung transplantation for patients with end-stage lung diseases is short, safe preservation time (4 to 6 hours). Our goal is to extend this to 24 hours or more, which would greatly improve clinical lung transplantation. METHODS We used the isolated perfused rat

2,3-Butanedione monoxime cardioplegia: advantages over hyperkalemia in blood-perfused isolated hearts.

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BACKGROUND 2,3-Butanedione monoxime (BDM) has been shown to possess cardioprotective properties related to the inhibition of cross-bridge force development, the reduction of myofilament Ca2+ sensitivity, and the attenuation of intracellular Ca2+ transients. This study tested the hypothesis that
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