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calciphylaxis/phosphatase

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ČlanciKlinička ispitivanjaPatenti
Stranica 1 iz 16 rezultatima

The role of pyrophosphate and alkaline phosphatase in skin calcification (calciphylaxis).

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Local calciphylaxis in dihydrotachysterol-sensitized rats. The role of alkaline phosphatase.

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Two cases of calciphylaxis treated by parathyroidectomy: importance of increased bone formation.

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Calciphylaxis (calcific uremic arteriolopathy) is a poorly understood and highly morbid syndrome of both vascular calcification and skin necrosis. The main histopathological finding is calcium deposits within arteriolar and small vessel walls, showing endovascular fibrosis associated with fat

Calciphylaxis associated with acute, reversible renal failure in the setting of alcoholic cirrhosis.

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We describe a case of calciphylaxis in a 47-year-old man with alcohol-induced end-stage liver disease and acute renal failure secondary to hepatorenal syndrome. Possible contributing factors included transiently impaired renal function, protein C and S deficiencies, elevated calcium-phosphate

A case report of severe calciphylaxis - suggested approach for diagnosis and treatment.

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BACKGROUND Calciphylaxis is a serious complication in patients with chronic kidney disease associated mineral and bone disorder. It can occur in conditions with low and high bone turnover. So far, there are no definite diagnostic and therapeutic guidelines which may prevent the devastating outcome

Risk factors and mortality associated with calciphylaxis in end-stage renal disease.

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BACKGROUND We conducted a case control study to determine risk factors and mortality associated with calciphylaxis in end-stage renal disease. METHODS Cases of calciphylaxis diagnosed between December 1989 and January 2000 were identified. Three controls were identified for each hemodialysis

Calcific uraemic arteriolopathy (calciphylaxis): data from a large nationwide registry.

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Calcific uraemic arteriolopathy (CUA, calciphylaxis) is a rare disease predominantly in dialysis patients and associated with high mortality. Painful skin ulcerations and calcification of cutaneous arterioles characterize calciphylaxis. We established an observational, Internet-based registry

Calciphylaxis in patients on hemodialysis: a prevalence study.

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BACKGROUND Calciphylaxis is characterized by painful, violaceous, mottled skin lesions (livedo reticularis) that may progress to tissue necrosis, nonhealing ulcers, gangrene, and potentially amputation, sepsis, or death. The prevalence and characteristics of patients who have calciphylaxis need

A case-control study of calciphylaxis in Japanese end-stage renal disease patients.

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BACKGROUND Calciphylaxis, also called calcific uremic arteriolopathy, is a rare and often fatal complication of end-stage renal disease and is characterized by painful skin ulceration, necrosis, medial calcification and intimal proliferation of small arteries. Studies in western countries have

[Calciphylaxis].

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METHODS Acute, zigzag-shaped livid skin markings developed on both thighs of a 55-year-old woman who had been on dialysis for 6 years. Within 7 days these areas increased in size to about 10 cm in diameter and contained central dry and painful necroses. On legs, lower arms and hands hard

Refractory renal hyperparathyroidism: clinical features and outcome of surgical therapy.

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Despite improvements in medical management parathyroidectomy has an important role in treatment of refractory renal hyperparathyroidism (HPT). The medical records of all patients who underwent parathyroidectomy from 1991 through 2000 were reviewed to determine the clinical and laboratory features

Effects of parathyroidectomy on tumoral calcinosis in uremic patients with secondary hyperparathyroidism.

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Tumoral calcinosis (TC) is a rare disease derived from uremic secondary hyperparathyroidism (SHPT). However, parathyroidectomy (PTX) seems to be ineffective at relieving TC in some patients. In this study, we investigated the relationship between PTX and TC

Outcomes of cinacalcet withdrawal in Australian dialysis patients.

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BACKGROUND Secondary hyperparathyroidism (SHPT) in chronic kidney disease is associated with cardiovascular and bone pathology. Measures to achieve parathyroid hormone (PTH) target values and control biochemical abnormalities associated with SHPT require complex therapies, and severe SHPT often

Vascular calcification in skin and subcutaneous tissue in patients with chronic and end-stage kidney disease

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Background: Vascular calcification (VC) is well described in large- and medium-sized vessels in patients with chronic kidney disease (CKD), especially in those with end-stage kidney disease (ESKD) on dialysis. Medial calcification is

Secondary hyperparathyroidism in children with chronic renal failure: pathogenesis and treatment.

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Despite advances in the management of patients with chronic renal failure, histologic features associated with secondary hyperparathyroidism remain the predominant skeletal findings; however, over the last decade the prevalence of adynamic bone has increased in both adult and pediatric patients with
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