cystic fibrosis/carbohydrate

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Sialylation and sulfation of the carbohydrate chains in respiratory mucins from a patient with cystic fibrosis.

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Mucin glycopeptides were prepared from the sputum of a patient suffering from cystic fibrosis. The carbohydrate chains were released by alkaline borohydride treatment. Sialylated and sulfated oligosaccharide-alditols were purified by ion-exchange chromatography, gel filtration, and high performance

Glycemic response to dietary supplements in cystic fibrosis is dependent on the carbohydrate content of the formula.

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BACKGROUND Enteral formula feedings are frequently prescribed to cystic fibrosis (CF) patients to boost caloric intake. A substantial number of these patients are glucose intolerant and have severe respiratory compromise. METHODS To determine the effect of the carbohydrate content on glucose

Increased serum concentrations of carbohydrate-deficient transferrin (CDT) in patients with cystic fibrosis.

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Carbohydrate-deficient transferrin (CDT) has been reported to be one of the best laboratory markers in serum (S) for detection of alcohol abuse. We have studied S-CDT values in cystic fibrosis (CF) patients and show that CF patients have increased S-CDT values without high alcohol consumption. CF

Comparison of low, medium, and high carbohydrate formulas for nighttime enteral feedings in cystic fibrosis patients.

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This study examined whether the increase in CO2 production (VCO2) and ventilatory demands by carbohydrate loading with different formulas during nighttime enteral feedings could be detrimental in young adult cystic fibrosis patients with moderate to advanced lung disease. Ten patients age 17 to 24

Glucose intolerance with low-, medium-, and high-carbohydrate formulas during nighttime enteral feedings in cystic fibrosis patients.

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Ten young adult cystic fibrosis (CF) patients over 16 years of age (average 21.4 years) began nighttime enteral feedings as a method of nutritional rehabilitation to regain and maintain body weight. Patients received nighttime feedings of 1,000 kcal/M2 of a low- (Pulmocare), medium- (Ensure Plus),

The carbohydrate content of IgG from patients with cystic fibrosis.

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We compare the complete carbohydrate composition of IgG purified from the serum of patients with cystic fibrosis (CF) with that of control subjects. Our results indicate that IgG from cystic fibrosis patients is underglycosylated with respect to galactose and sialic acid, the two terminal sugars on

Carbohydrate metabolism changes in cystic fibrosis.

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OBJECTIVE To assess the prevalence of impaired glucose tolerance (ITG) and diabetes mellitus (DMRCF) in a group of patients with cystic fibrosis (CF). To study clinical status-related variables and to compare age with the evolution of their carbohydrate metabolism (CHM). METHODS Thirty patients with

Immunohistochemical investigation with carbohydrate monoclonal antibodies in cystic fibrosis.

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BACKGROUND Cystic fibrosis is one of the most common inherited diseases in Europe. In patients with cystic fibrosis, the serum levels of the tumour marker antigens CA19-9 and CA50, which are normally found in the epithelium of many organs, are increased. No such finding has been reported for CA242,

Cystic fibrosis. Carbohydrate metabolism in CF and in animal models for CF.

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Cystic fibrosis (CF) is a chronic genetic disease mainly affecting the exocrine glands. Its main clinical symptoms are: abnormal production of mucus which blocks the airways, pancreatic insufficiency and increased sweat electrolytes. In the present investigation a series of enzymes and

Carbohydrate tolerance in cystic fibrosis is closely linked to pancreatic exocrine function.

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We evaluated carbohydrate tolerance in nine thin cystic fibrosis (CF) patients and in six controls, measuring responsiveness to the following insulinotropic secretagogues: oral glucose, IV glucose, and IV tolbutamide. Glucose responses segregated patients into two groups: Group I with normal

Comparison of the carbohydrate composition of alpha 2-macroglobulin from patients with cystic fibrosis and normal controls.

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The putative involvement of alpha 2-macroglobulin (alpha 2M) in the pathogenesis of cystic fibrosis has long been a subject of controversy. Previous reports have indicated that there are alterations in the carbohydrate moieties of alpha 2M in the disease. In the present study the carbohydrate

Carbohydrate intake and insulin requirement in children, adolescents and young adults with cystic fibrosis-related diabetes: A multicenter comparison to type 1 diabetes.

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OBJECTIVE In cystic fibrosis-related diabetes (CFRD), energy needs differ from type 1 (T1D) or type 2 diabetes, and endogenous insulin secretion is not totally absent. We analyzed whether daily carbohydrate intake, its diurnal distribution and insulin requirement per 11 g of carbohydrate differ

[Carbohydrate metabolic changes in cystic fibrosis].

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OBJECTIVE To assess the prevalence of impaired glucose tolerance and diabetes mellitus in a group of patients with cystic fibrosis and to compare insulin secretion, haemoglobin A1c, age, gender, genotype, and clinical status related variables between the groups with abnormal (impaired glucose

Carbohydrate malabsorption is minimal in school-age cystic fibrosis children.

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Fifteen school-age cystic fibrosis children, participating in a year-long nutritional management study, were hospitalized at six-month intervals for balance studies during which they continued "free-choice" diets and their usual enzyme supplementation. Stools were analyzed for fat and protein by

Carbohydrate counting accuracy in adults with cystic fibrosis related diabetes.

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Poorly controlled Cystic Fibrosis-Related Diabetes (CFRD) is associated with adverse impacts on lung function and nutritional status. Insulin therapy is the only recommended medical treatment. Carbohydrate Counting (CC) is used to guide insulin doses and can assist in achieving optimal

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