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diterpene lactone/rak dojke
Veza se sprema u međuspremnik
3 rezultatima
Induction of heme oxygenase-1 and inhibition of TPA-induced matrix metalloproteinase-9 expression by andrographolide in MCF-7 human breast cancer cells.
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Prijava Registriraj se
Matrix metalloproteinase-9 (MMP-9) plays a critical role in cancer metastasis. Andrographolide (AP) is a diterpene lactone in the leaves and stem of Andrographis paniculata (Burm. f) Ness that has been reported to possess anticancer activity. In this study, we investigated the effect of AP on
mPEG-PLA Micelle for Delivery of Effective Parts of Andrographis Paniculata.
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BACKGROUND
Many studies have shown that Andrographis paniculata (Burm. f.) Nees has a good anti-tumor effect, but poor solubility in water and poor bioavailability hinder the modernization of it.
METHODS
To formulate the effective parts (mainly diterpene lactones) of Andrographis paniculata (AEP)
Anticancer activity of andrographolide semisynthetic derivatives.
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Andrographolide 1, a diterpene lactone of Andrographis paniculata, displays in vitro and in vivo antitumor activity against breast cancer models and mouse myeloid leukemia (M1) cells. In the present study, we report the semi-synthesis of andrographolide derivatives and their in vitro activity
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