drug eruptions/glutation

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Glutathione S-transferase polymorphisms in patients with photosensitive and non-photosensitive drug eruptions.

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Prijava Registriraj se

Glutathione S-transferases (GSTs) play a critical role in cellular protection against oxidative damage. Polymorphisms in three major GST loci have been described. A number of studies have looked for an association between GSTs and skin diseases.To ascertain

Glutathione S-transferase polymorphisms in patients with drug eruption.

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Prijava Registriraj se

Glutathione S-transferase (GST) enzymes play an important role in drug metabolism. GST is a multigene family of enzymes involved in the detoxification and in a few instances activation of a wide variety of chemicals. Detoxification features make it plausible to search for GST polymorphism in

Oxidative stress and leukocyte migration inhibition response in cutaneous adverse drug reactions.

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Prijava Registriraj se

BACKGROUND Cutaneous adverse drug reactions (CADRs) may either be immunological or non-immunological. The precise mechanisms, however, are largely obscure. Other concomitant mechanisms may amplify and/or contribute to the severity and duration of a reaction. One such mechanism could be oxidative

Prospective evaluation of risk factors of cutaneous drug reactions to sulfonamides in patients with AIDS.

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BACKGROUND Persons with HIV infection have increased rates of drug eruptions. OBJECTIVE Our aim was to evaluate the risk factors of drug eruptions in response to sulfonamides in patients with AIDS, using a case-control analysis. METHODS One hundred thirty-six patients who were hospitalized for

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