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SRM assay to indicate cancer therapy

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INTRODUCTION Lung cancer is the most prevalent cancer (>200,000 new US cases/year) and has a low five-year survival rate (.about.15%). Therapy for lung cancer is transitioning from use of a limited selection of therapies, consisting of radiation, folate metabolism, platinum-based drugs, and/or

Multiplex MRM assay for evaluation of cancer

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INTRODUCTION Specific peptides derived from subsequences of the estrogen receptor (ER), the progesterone receptor (PR), and the antigen Ki67 (Ki67) proteins are provided. The peptide sequences and fragmentation/transition ions for each peptide are particularly useful in a mass spectrometry-based

Multiplex MRM assay for evaluation of cancer

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Contrast resolution tissue mimicking phantoms for nuclear magnetic resonance imaging with stable NMR properties

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FIELD OF THE INVENTION This invention pertains generally to products and techniques for testing the resolution capabilities of nuclear magnetic resonance (NMR) imaging equipment and particularly to imaging processes in which hydrogen is the monitored nucleus. BACKGROUND OF THE INVENTION The early

Bioactive acetogenins and derivatives

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FIELD OF INVENTION This invention relates to the isolation, identification, derivatization, and use of natural products. More particularly this invention is directed to substantially pure forms of cytotoxic Annonaceous acetogenins and certain ester and cyclized ether acetogenin

Bioactive acetogenins and derivatives

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Cyclin-dependent protein kinases inhibitors of Scutellaria flavonoid organic amine derivatives, synthesis and use thereof

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FIELD OF THE INVENTION The present invention relates to the field of drug synthesis. More particularly, it relates to synthesis of a series of cyclin-dependent protein kinases inhibitors, Scutellaria flavonoid organic amine derivatives, and their potential applications in anti-cancer and

Alpha-(3,5-dimethoxybenzylidene)-alpha'-hydrocarbyl methylene cyclic ketone and preparation method thereof

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FIELD OF THE INVENTION The present invention is related to the field of antitumor agents, in particular to a .alpha.-(3,5-dimethoxybenzylidene)-.alpha.'-hydrocarbyl methylene cyclic ketone and preparation method thereof. BACKGROUND OF THE INVENTION Cancer has become one of major diseases which are

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