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gastrinoma/tyrosine
Veza se sprema u međuspremnik
4 rezultatima
Effects of the tyrosine kinase inhibitor imatinib on neuroendocrine tumor cell growth.
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Prijava Registriraj se
OBJECTIVE
We investigated the effects of the tyrosine kinase inhibitor imatinib (Gleevec) on neuroendocrine tumor cells.
METHODS
Neuroendocrine tumor cells were incubated without and with imatinib. The effects on growth were examined by methylthiazoletetrazolium (MTT) assay. The c-Kit expression in
Bombesin stimulates the in vitro growth of a human gastric cancer cell line.
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Prijava Registriraj se
Bombesin (BBS) and its mammalian equivalent, gastrin-releasing peptide (GRP), exhibit diverse biological functions, including that of a neurotransmitter, a regulator of gastrointestinal hormone release, and a trophic factor for various normal and neoplastic tissues. Bombesin stimulates the growth of
Pancreatic neuroendocrine tumors: approach to treatment with focus on sunitinib.
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Prijava Registriraj se
Pancreatic neuroendocrine tumors (pNETs) are relatively rare malignancies. With secretory tumors such as insulinomas, vasoactive intestinal peptideomas, and gastrinomas, the hormone produced causes the symptom complex (e.g. hypoglycemia, peptic ulcer disease). With nonsecretory NETs, the clinical
Growth factor receptor expression in human gastroenteropancreatic neuroendocrine tumours.
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Prijava Registriraj se
BACKGROUND
Human gastroenteropancreatic neuroendocrine tumours are functionally and biologically heterogeneous, but their exact growth factor receptor expression pattern, important for onco- and carcinogenesis, remains unknown.
METHODS
This study searched for the mRNA expression pattern of six
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