Epilepsies, Partial

automated analysis of surface EEG with electrocal source imaging

electrical source imaging

Saint-Luc University Hospital

Centre Hospitalier William Lennox

Added Value of Automated Electrical Source Localization (EPILOG PreOp®) to Presurgical Evaluation of Refractory Epilepsy

What is the Added Clinical Value of an Automated EEG Analysis Program With Electrical Source Localization (EPILOG PreOp®) as Part of the Pre-surgical Assessment of Non-lesional Refractory Epilepsy?

Descriptive analysis of population with results from Epilog Preop analysis that changed initial clinical decision (total number of patients, type management plan modification)

Are Epilog+ results in the same location as the resection zone?

Are Epilog+ results identifying abnormal cortex?

What proportion of patients are seizure free if Epilog+ results are resected; what proportion of patients are not seizure free if Epilog + results are not resected?

Are results obtained with Epilog Preop from high density EEG better?

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

All patients included will have Epilog Preop analysis

Investigator has no access to Epilog Preop result during first case description.

Twenty five (25) healthy individuals of same age group will serve as the control group. Control subjects will be evaluated at baseline only.

Twenty five (25) patients recruited in this group will receive Tab. Carbamazepine. Carbamazepine will be started with a dose of 200 mg/day for one week and then increased to 400 mg/day for one week and then 600mg/day for next two weeks.

Twenty five (25) patients recruited in this group will receive Tab. Oxcarbazepine. Oxcarbazepine will be started with 10mg/kg daily dose for one week followed by 15mg/kg daily for next one week and then will be increased to 20mg/kg for next two weeks.

Seizures, Focal

Carbamazepine will be started with a dose of 200 mg/day for one week and then increased to 400 mg/day for one week and then 600mg/day for next two weeks.

Carbamazepine

Oxcarbazepine will be started with 10mg/kg daily dose for one week followed by 15mg/kg daily for next one week and then will be increased to 20mg/kg for next two weeks.

Oxcarbazepine

AIIMS, Bhubaneswar

Effect of Carbamazepine and Oxcarbazepine on Serum Neuron-specific Enolase and S100B in Focal Seizures

The scale was developed at the Chalfont Centre for Epilepsy based on the Chalfont Seizure Severity Scale. It can be used to measure the severity of the seizures and to evaluate anti-epileptic agents during clinical trials.

Quality of Life in Epilepsy Inventory (QOLIE-31) contains seven multi-item scales that tap the following health concepts: emotional well-being, social functioning, energy/fatigue, cognitive functioning, seizure worry, medication effects, and overall quality of life. A QOLIE31 overall score is obtained using a weighted average of the multi-item scale scores.

RITUPARNA MAITI

Associate Professor

All India Institute of Medical Sciences, Bhubaneswar

Post-Hemorrhagic Hydrocephalus

University of Utah

Cerebral Perfusion, Oxygenation, Electrical Activity

Alterations in Cerebral Perfusion, Oxygenation, Electrical Activity, and Markers of Cerebral Damage Associated With Cerebro-spinal Fluid Reservior Aspiration in Neonates With Post Hemorrhagic Hydrocephalus

Joanna Beachy Ph.D., M.D.

Chronic Focal Encephalitis

Rasmussen's Encephalitis

375 mg/m2 given as an IV infusion once weekly for four doses

gliosis/seizures

Added Value of Automated Electrical Source Localization (EPILOG PreOp®) to Presurgical Evaluation of Refractory Epilepsy

Effect of Carbamazepine and Oxcarbazepine on Serum Neuron-specific Enolase and S100B in Focal Seizures

Cerebral Perfusion, Oxygenation, Electrical Activity

A Pilot Study of the Use of Rituximab in the Treatment of Chronic Focal Encephalitis

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