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hexanol/sarcoma

Veza se sprema u međuspremnik
ČlanciKlinička ispitivanjaPatenti
3 rezultatima

Targeting Glutathione S-transferase M4 in Ewing sarcoma.

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Prijava Registriraj se
Ewing sarcoma is a malignant pediatric bone and soft tissue tumor. Although the 5-year survival rate of localized disease approaches 75%, the prognosis of metastatic and/or therapy-resistant disease remains dismal despite the wide use of aggressive therapeutic strategies. We previously reported that

Overcoming resistance to conventional drugs in Ewing sarcoma and identification of molecular predictors of outcome.

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Prijava Registriraj se
OBJECTIVE The improvement of Ewing sarcoma (EWS) therapy is currently linked to the discovery of strategies to select patients with poor and good prognosis and of modified treatment regimens. In this study, we analyzed the molecular factors governing EWS response to chemotherapy to identify genetic

Targeting glutathione-S transferase enzymes in musculoskeletal sarcomas: a promising therapeutic strategy.

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Prijava Registriraj se
Recent studies have indicated that targeting glutathione-S-transferase (GST) isoenzymes may be a promising novel strategy to improve the efficacy of conventional chemotherapy in the three most common musculoskeletal tumours: osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma. By using a panel of 15
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