3 rezultatima
OBJECTIVE
To investigate the antitumor activity of mice bearing sarcoma 180 cell lines treated with indican of Indigofera suffruticosa and the histological and morphometric analysis on the liver of those animals.
METHODS
The mice were divided into 3 groups: Group 1 (G1) and Group 3 (G3) bearing
The plant Polygonum tinctorium produces the secondary metabolite indican (indoxyl-β-D-glucoside), a precursor of the blue dye indigo. P. tinctorium synthesizes indican through the actions of the UDP-glucosyltransferase (UGT), indican synthase. Herein, we partially purified an indican synthase from
Indican is a secondary metabolite in Indigofera tinctoria; its synthesis from indoxyl and UDP-glucose is catalyzed by a UDP-glucosyltransferase (UGT). In this study, we partially purified UGT extracted from I. tinctoria leaves and analyzed the protein by peptide mass fingerprinting. We identified