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inokosterone/achyranthes
Veza se sprema u međuspremnik
13 rezultatima
[Isolation and structure identification of C-25 epimers of inokosterone from Achyranthes bidentata Blume].
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OBJECTIVE
To isolate C-25 epimers of inokosterone from Achyranthes bidentata Blume. and identify their structures.
METHODS
To separate C-25 epimers of inokosterone by using various kinds of chromatography methods and identify their structures on basis of spectral analysis and chemical
[Biosynthesis of inokosterone and ecdysterone from cholesterol and mevalonic acid in Achyranthes (author's transl)].
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Metabolomic investigation on fermentation products of Achyranthes japonica Nakai by Lactobacillus plantarum.
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Fermentation has recently re-emerged as an approach for improved functionality of food products in addition to the traditional roles such as shelf life, taste, and texture. Here, we report dynamic changes in metabolite profiles of the Achyranthes japonica Nakai by Lactobacillus
[Study on the fingerprints of Achyranthes bidentata Bl. by HPLC/UV/MS].
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OBJECTIVE
To establish the fingerprints of Achyranthes bidentata Bl. by HPLC/UV/MS.
METHODS
Separation was performed on Aglient Zorbax SB-C18 column. Gradient elute was performed by the mobile phase consisting of methanol and 0.1% formic acid-water with the flow rate of 1.0 ml/min.
RESULTS
Perfect
[Determination of ecdysones in polyploid and monoploid Achyranthes bidentata Bl].
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Total ecdysones (ecdysterone and inokosterone) were isolated and identified from Achyranthes bidentata radix of polyploid and monoploid by column chromatography. The hormone contents of monoploid and diploid are about the same, but the content of polyploid is 14 times that of the diploid.
Development and validation of an UHPLC-MS/MS approach for simultaneous quantification of five bioactive saponins in rat plasma: Application to a comparative pharmacokinetic study of aqueous extracts of raw and salt-processed Achyranthes bidentata.
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A simple, accurate and sensitive ultra high-performance liquid chromatography-tandem mass spectrometry approach was established for the simultaneous determination of β-ecdysterone, 25S-inokosterone, ginsenoside Ro, chikusetsusaponin IV and chikusetsusaponin IVa in rat plasma after oral
Identification of candidate synovial membrane biomarkers after Achyranthes aspera treatment for rheumatoid arthritis.
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Rheumatoid arthritis (RA) is a systemic autoimmune disease whose main symptom is a heightened inflammatory response in synovial tissues. To verify the anti-arthritic activities of Achyranthes aspera and its possible therapy-related factors on the pathogenesis of RA, the saponins in A. aspera root
Tissue-based metabolite profiling and qualitative comparison of two species of Achyranthes roots by use of UHPLC-QTOF MS and laser micro-dissection.
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Achyranthes bidentata and Achyranthes aspera are saponin and steroid rich medicinal plants, used extensively for therapeutic treatments in Traditional Chinese Medicine (TCM) and Ayurveda. A. bidentata is reported to be one of the rare and extensively exploited medicinal plant species that face the
Phytoecdysteroids from the roots of Achyranthes bidentata Blume.
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Two new phytoecdysteroids, (25S)-20,22-O-(R-ethylidene)inokosterone and 20,22-O-(R-3-methoxycarbonyl)propylidene-20-hydroxyecdysone, together with six known phytoecdysteroids 3-8 were isolated from the roots of Achyranthes bidentata Blume. The new structures were established on the basis of
Raw and salt-processed Achyranthes bidentata attenuate LPS-induced acute kidney injury by inhibiting ROS and apoptosis via an estrogen-like pathway
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Background: Traditional Chinese medicine suggests that Radix Achyranthis Bidentatae nourishes and protects the kidneys, the effect of which is enhanced following a salt treatment. Raw and salt-processed Achyranthes bidentata are produced
A liquid chromatography-tandem mass spectrometry approach for study the tissue distributions of five components of crude and salt-processed Radix Achyranthes in rats.
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This study developed a robust and reliable approach using liquid chromatography- tandem mass spectrometry for the simultaneous determination of five saponins in rat tissues: β-ecdysterone, chikusetsusaponin IV, ginsenoside Ro, 25S-inokosterone and chikusetsusaponin IVa. This is the first report on a
Determination of major components from Radix Achyranthes bidentate using ultra high performance liquid chromatography with triple quadrupole tandem mass spectrometry and an evaluation of their anti-osteoporosis effect in vitro.
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Ecdysterone and saponins are the most characteristic components of Radix Achyranthes bidentate, which acts on the human body to promote collagen synthesis and stimulates cell growth. However, the relationship between these components and the differentiation of MC3T3-E1 osteoblastic cells is unknown.
High performance liquid chromatography used for quality control of Achyranthis Radix.
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To establish a standard of quality control and to identify reliable Achyranthis Radix, three phytoecdysones including ecdysterone (1), 25R-inokosterone (2) and 25S-inokosterone (3) were determined by quantitative HPLC/UV analysis. Three phytoecdysones were separated with an YMC J'sphere ODS C(18)
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