4 rezultatima
The effects of the extract of the bark of Mahonia aquifolium and its main constituents (berberine, berbamine, oxyacanthine) on 5-lipoxygenase, lipid peroxidation in phospholipid liposomes induced by 2,2'-azo-(bis-2-amidinopropane), deoxyribose degradation, and their reactivities against the free
The extract of the bark of Mahonia aquifolium is an inhibitor of keratinocyte growth with an IC50 of 35 microM. Of its main alkaloids tested, berberine inhibited cell growth to the same extent as did the Mahonia extract, while the benzylisoquinoline alkaloids berbamine and oxyacanthine were more
Alcoholic extracts of the antipsoriatic Mahonia aquifolium drug which were analysed for their qualitative and quantitative alkaloid content, showed an in vitro inhibiting effect on cyclo-oxygenase (CO) of sheep seminal vesicles and 5-lipoxygenase (5-LO) of porcine leucocytes. The same extracts
Psoriasis vulgaris is a skin disease with a multi-factorial genesis where no causal treatment is known. Based on our own pilot studies, we set up a randomized, placebo-controlled clinical trial to evaluate the efficacy and safety of Mahonia aquifolium bark extract in psoriasis patients. From autumn