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Stranica 1 iz 290 rezultatima
Variations in potassium channel genes are associated with distinct trajectories of persistent breast pain after breast cancer surgery.
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Persistent pain after breast cancer surgery is a common clinical problem. Given the role of potassium channels in modulating neuronal excitability, coupled with recently published genetic associations with preoperative breast pain, we hypothesized that variations in potassium channel genes will be
Preoperative Breast Pain Predicts Persistent Breast Pain and Disability After Breast Cancer Surgery.
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BACKGROUND
Approximately 30% of the women report pain in the affected breast before breast cancer surgery.
OBJECTIVE
The purpose of this secondary analysis of our prospective study was to determine how women who experienced both preoperative and persistent postsurgical breast pain (n=107) differed
Cyclical mastalgia and breast cancer risk: results of a French cohort study.
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Cyclical mastalgia is a common complaint, with a potentially important relationship to breast cancer risk. In the last decade, case-control studies have reported that cyclical mastalgia could be considered as an independent risk factor for breast cancer. The subjectivity of a retrospectively
Persistent breast pain 5 years after treatment of invasive breast cancer is largely unexplained by factors associated with treatment.
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OBJECTIVE
The aim of our study was to establish the prevalence of breast pain persisting 5 years after the initial treatment of breast cancer (BC) and the relationship between those persistent symptoms and general well-being.
METHODS
The study involved women from Victoria, Australia, who had
Mastalgia and breast cancer: a protective association?
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Breast pain (mastalgia) is a common complaint, with a potentially important relationship to breast cancer risk. We have examined the association between mastalgia and breast cancer in the patient population of the Breast Care Center of University Hospital, Syracuse, New York. Of 5463 women with
Mastalgia and breast tumour in Nigerian women.
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376 Nigerian women who presented with histologically proved breast tumour (256 benign and 120 malignant) were admitted to a study of mastalgia and breast tumour. A total of 67 patients, consisting of 57 (22.3%) of 256 benign disease patients and 10 (8.3%) of 120 malignant disease patient had pain,
Localized mastalgia as presenting symptom in breast cancer.
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The importance of breast pain as a presenting symptom of breast cancer was assessed in 200 women with localized mastalgia but negative physical examination and in 478 women with operable breast cancer. In the first group, mammography detected five cases of subclinical breast cancer at the site of
Estimated breast cancer risk and screening outcomes among premenopausal women with non-cyclic mastalgia.
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OBJECTIVE
Breast pain is a common but worrisome symptom, which can cause a significant psychological burden of cancer stress. It is not known whether breast cancer risk estimation models can be used as an adjunct to the clinical and radiological assessment in counseling women with mastalgia. The aim
Associations between cytokine gene variations and severe persistent breast pain in women following breast cancer surgery.
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Persistent pain following breast cancer surgery is a significant clinical problem. Although immune mechanisms may play a role in the development and maintenance of persistent pain, few studies have evaluated for associations between persistent breast pain following breast cancer surgery and
Importance of mastalgia in operable breast cancer.
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The importance of pain as a presenting symptom of breast cancer has been assessed in a series of 240 patients with operable breast cancer over four years. From an analysis of the case histories of 36 patients the diagnosis proved difficult in one-quarter of the cancers. This is explained by the high
Cyclical mastalgia as a marker of breast cancer susceptibility: results of a case-control study among French women.
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A matched case-control study in a population of urban, non-menopaused women living in Paris was performed between 1983 and 1985 to investigate the risk of breast cancer (BC) in relation to various factors with a particular interest in the effect of the use of oral contraceptive (OC) and the
Variations in potassium channel genes are associated with breast pain in women prior to breast cancer surgery.
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Preoperative breast pain in women with breast cancer may result from a number of causes. Previous work from our team found that breast pain occurred in 28.2% of women (n = 398) who were about to undergo breast cancer surgery. The occurrence of preoperative breast pain was associated with a number of
Persistent arm pain is distinct from persistent breast pain following breast cancer surgery.
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Persistent pain following breast cancer surgery is well documented. However, it is not well characterized in terms of the anatomic site affected (ie, breast, arm). In 2 separate growth mixture modeling analyses, we identified subgroups of women (N = 398) with distinct breast pain and arm pain
Persistent breast pain following breast cancer surgery is associated with persistent sensory changes, pain interference, and functional impairments.
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Interindividual variability exists in persistent breast pain following breast cancer surgery. Recently, we used growth mixture modeling to identify 3 subgroups of women (N = 398) with distinct persistent breast pain trajectories (ie, mild, moderate, severe) over 6 months following surgery. The
Mastalgia; is this commonly associated with operable breast cancer?
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A detailed analysis by questionnaire of breast pain in 460 newly referred patients at a specialized breast clinic revealed that only 1.5% of patients with pain had an early breast cancer. Of all 44 cancers 8 were painful but only 4 considered early. All these had nipple retraction. We conclude that
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