methional/carcinogenesis

Veza se sprema u međuspremnik

ČlanciKlinička ispitivanjaPatenti

Odaberite vrstu sortiranja

7 rezultatima

Metabolism of carcinogenic urethane to nitric oxide is involved in oxidative DNA damage.

Samo registrirani korisnici mogu prevoditi članke

Prijava Registriraj se

Carcinogenic urethane (ethyl carbamate) forms DNA adduct via epoxide, whereas carcinogenic methyl carbamate can not. To clarify a mechanism independent of DNA adduct formation, we examined DNA damage induced by N-hydroxyurethane, a urethane metabolite, using 32P-5'-end-labeled DNA fragments.

Site-specific DNA damage induced by nickel(II) ion in the presence of hydrogen peroxide.

Samo registrirani korisnici mogu prevoditi članke

Prijava Registriraj se

DNA damage induced by Ni(II) plus H2O2 was investigated by a DNA sequencing technique using 32P-5'-end-labeled DNA fragments obtained from human c-Ha-ras-1 protooncogene. Ni(II) induced strong DNA cleavage in the presence of H2O2 even without piperidine treatment. Piperidine-labile sites were

Metabolic activation of carcinogenic ethylbenzene leads to oxidative DNA damage.

Samo registrirani korisnici mogu prevoditi članke

Prijava Registriraj se

Ethylbenzene is carcinogenic to rats and mice, while it has no mutagenic activity. We have investigated whether ethylbenzene undergoes metabolic activation, leading to DNA damage. Ethylbenzene was metabolized to 1-phenylethanol, acetophenone, 2-ethylphenol and 4-ethylphenol by rat liver microsomes.

Human DNA damage induced by 1,2,4-benzenetriol, a benzene metabolite.

Samo registrirani korisnici mogu prevoditi članke

Prijava Registriraj se

Reactivities of benzene metabolites (phenol, catechol, hydroquinone, 1,4-benzoquinone, 1,2,4-benzenetriol) and related polyphenols (resorcinol, pyrogallol, phloroglucinol) with DNA were investigated by a DNA sequencing technique using 32P 5'-end-labeled DNA fragments obtained from human c-Ha-ras-1

Requirement of glutathione and cysteine in guanine-specific oxidation of DNA by carcinogenic potassium bromate.

Samo registrirani korisnici mogu prevoditi članke

Prijava Registriraj se

Potassium bromate (KBrO3), a food additive, induces renal-cell tumors in rats. KBrO3 induced 8-oxo-7, 8-dihydro-2'-deoxyguanosine (8-oxodG) formation in human leukemia cell line HL-60 as well as in its H2O2-resistant clone, HP100, suggesting no involvement of H2O2. Depletion of GSH by buthionine

Mechanism of metal-mediated DNA damage induced by metabolites of carcinogenic 2-nitropropane.

Samo registrirani korisnici mogu prevoditi članke

Prijava Registriraj se

2-Nitropropane (2-NP), a widely used industrial solvent, is carcinogenic to rats. To clarify the mechanism of carcinogenesis by 2-NP, we investigated DNA damage by 2-NP metabolites, N-isopropylhydroxylamine (IPHA) and hydroxylamine-O-sulfonic acid (HAS), using 32P-5'-end-labelled DNA fragments

Hydroxyurea induces site-specific DNA damage via formation of hydrogen peroxide and nitric oxide.

Samo registrirani korisnici mogu prevoditi članke

Prijava Registriraj se

Hydroxyurea is a chemotherapeutic agent used for the treatment of myeloproliferative disorders (MPD) and solid tumors. The mutagenic and carcinogenic potential of hydroxyurea has not been established, although hydroxyurea has been associated with an increased risk of leukemia in MPD patients. To

Pridružite se našoj
facebook stranici

Herbal & Natural Medicine

Najkompletnija baza ljekovitog bilja potpomognuta znanošću

Radi na 55 jezika
Biljni lijekovi potpomognuti znanošću
Prepoznavanje bilja slikom
Interaktivna GPS karta - označite bilje na mjestu (uskoro)
Pročitajte znanstvene publikacije povezane s vašom pretragom
Pretražite ljekovito bilje po učincima
Organizirajte svoje interese i budite u toku s istraživanjem vijesti, kliničkim ispitivanjima i patentima

Upišite simptom ili bolest i pročitajte o biljkama koje bi mogle pomoći, unesite travu i pogledajte bolesti i simptome protiv kojih se koristi.
* Svi podaci temelje se na objavljenim znanstvenim istraživanjima