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We report the case of an ICU patient with previous medical history of head trauma with hydrocephalus requiring ventricular derivation, presenting a coma (Glasgow Coma Score=8) with bilateral mydriasis after the use of transdermal scopolamine (1 mg) for profuse bronchial secretions. Neurological
The authors report five cases of mydriasis induced by the use of transdermal scopolamine delivery systems. Anisocoria and narrow angle glaucoma were involved in four cases; in one case, the use of a strong dosage resulted in a bilateral mydriasis in a child.
Contamination of the eye after handling of a transdermal scopolamine patch may cause accidental mydriasis. A simple office test is discussed to identify this pharmacologic blockade and thereby avoid an extensive neurologic workup.
METHODS
We report the case of a patient who presented with unilateral mydriasis after a scopolamine patch application. The specific clinical context (cancer) reported here may have led to the misinterpretation of the etiology of mydriasis.
CONCLUSIONS
Our case description warns against diagnostic
Although scopolamine is rarely intentionally applied directly to the eye, accidental contamination can occur after touching or handling a transdermal scopolamine patch, worn behind the ear to prevent motion sickness, and then rubbing one's eyes or handling contact lenses. An acute episode of
Transdermal scopolamine may be used to reduce drooling in children with disabilities. Side-effects include dilated pupils and a reduction in the near point of accommodation (the closest point at which clear vision is possible). Two male children with epilepsy, one with spinal dysraphism (aged 7y
Acute anisocoria requires timely examination to rule out intracranial pathology. This case report describes a 34-year-old nurse who experienced blurred vision and unilateral mydriasis. She had no other complaints, and neurological examinations were normal. Shortly before, she had removed a
The authors present a case of unilateral mydriasis in a teenager prescribed transdermal hyoscine hydrobromide (scopolamine) for chemotherapy induced nausea and vomiting. The authors discuss the ocular side-effects associated with this particular drug and delivery system and the potential use of
OBJECTIVE
An epidemic of scopolamine poisonings occurred in Oslo in 2008 among users of illicit drugs, caused by fake Rohypnol pills. The clinical features, diagnostic process, and handling of the epidemic are presented.
METHODS
Suspected cases of scopolamine poisoning were extracted by reviewing