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3 rezultatima
Salutaridine N-Oxide from the Capsules of Papaver bracteatum.
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Prijava Registriraj se
A novel compound, salutaridine N-oxide ( 1) has been isolated from PAPAVER BRACTEATUM Lindl (Papaveraceae) in which the major alkaloids were salutaridine and thebaine. Semisynthetic 1 was prepared for structure confirmation. Other components of the alkaloidal fraction were isothebaine, oripavine,
Codeinone reductase isoforms with differential stability, efficiency and product selectivity in opium poppy.
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Prijava Registriraj se
Codeinone reductase (COR) catalyzes the reversible NADPH-dependent reduction of codeinone to codeine as the penultimate step of morphine biosynthesis in opium poppy (Papaver somniferum). It also irreversibly reduces neopinone, which forms by spontaneous isomerization in aqueous solution from
A microbial biomanufacturing platform for natural and semisynthetic opioids.
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Prijava Registriraj se
Opiates and related molecules are medically essential, but their production via field cultivation of opium poppy Papaver somniferum leads to supply inefficiencies and insecurity. As an alternative production strategy, we developed baker's yeast Saccharomyces cerevisiae as a microbial host for the
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