A medical article, such as a catheter, is formed from a blend of polyurethane and synthetic polyisoprene (SPIR). The blended medical article is preferably selected and prepared to be relatively rigid at room temperature and relatively flexible at body temperature. An intermittent catheter made from the blend provides a degree of stiffness for its insertion into the patient at room temperature. The catheter becomes softer, and therefore more comfortable, at warmer temperatures (e.g., body temperature) which reduce discomfort after insertion. Optionally, the catheter or a portion thereof can have a hydrophilic coating as to avoid the need for external lubricants. Advantageously, the blended catheter can meet the stiffness, tensile strength, and coefficient of friction requirements of intermittent catheterization applications while avoiding the risk of toxic or allergic reactions in sensitive users.

Bracken; Ronald L.

Chen; Fung Bor

Tuck; Randy

C.R. Bard, Inc.

Polyurethane/polyisoprene blend catheter

This invention relates to the method for fabrication of polyisoprene aqueous emulsion, gloves and related products thereof, wherein the aqueous emulsion is polyisoprene or polynitrile aqueous emulsion obtained through free-radical emulsion polymerization initiated by initiating agent under normal pressure with isoprene as the monomer, or isoprene monomer, acrylonitrile monomer, and (methyl)acrylic acid as the monomer mixture, and emulsifying agent and dispersing agent as the emulsification system. After the isoprene or the mixture of isoprene monomer, acrylonitrile monomer, and (methyl)acrylic acid is mixed with the initiating agent, the oil phase obtained together with reducing agent is added dropwise in different time quantums. The polymerization conversion rate of polyisoprene aqueous emulsion or polynitrile aqueous emulsion according to this invention is increased from the original 78% to over 97.5%. Fabricated polyisoprene or polynitrile gloves and thin latex products thereof have high strength and good extensibility, provide good hand touch, and do not cause allergies of the human body. They can be used for various purposes.

Shanghai Shengda Medical Application Co. Ltd.

Polyisoprene aqueous emulsion and a method to fabricate gloves and related products

A semi-synthetic rubber latex. The rubber employed in the latex is natural rubber obtained from plant life known to produce polyisoprene. Surprisingly, the semi-synthetic rubber latex is essentially devoid of those proteins that are known to give rise to natural rubber allergenicity or hypersensitivity, and are also essentially devoid of antigens that potentially will give rise to immune responses. Also provided is a method for obtaining the semi-synthetic rubber latex and dipped films thereof that are also substantially free of known natural rubber allergens.

polyisoprene/hypersensitivity

Polyurethane/polyisoprene blend catheter

Polyisoprene aqueous emulsion and a method to fabricate gloves and related products

Hypoallergenic natural rubber latex and a process for making the same

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