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Stranica 1 iz 23 rezultatima
[Vitamin C deficiency and leg ulcers. A case control study].
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Vitamin C is a necessary cofactor for collagen synthesis. A deficiency of vitamin C results in the breakdown of connective tissue in and around the walls of blood vessels. The disease is thus characterized by poor healing of wounds. Chronic leg ulcers are defined as wounds that do not
Interaction between aspirin and vitamin C with human serum albumin as binary and ternary systems.
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Foods generally contain special ingredients which easily to interact with drugs human intaking, thus affecting drug efficacy and excretion, and even cause adverse reactions. Vitamin C (Vit. C) is abundant in fresh fruits and vegetables. It plays a regulatory role in redox metabolism, and its absence
Vitamin C treatment reduces transcapillary escape rate of albumin in type 1 diabetes.
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BACKGROUND: Latent tissue scurvy in clinical and experimental ascorbic acid (AA) deficiency resembles diabetic microangiopathy as reflected in capillary hyperperfusion and increased transcapillary escape rate (TER), von Willebrand factor (vWf), and capillary fragility (CF). We aimed to investigate
Scurvy in hospitalized elderly patients.
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OBJECTIVE
The aim of this study was to systematically screen hospitalized elderly patients for clinical symptoms of scurvy and to confirm the diagnosis with biological measures.
METHODS
Geriatric acute care ward.
METHODS
Scurvy symptoms (one or more among perifollicular hyperkeratosis, petechiae or
Vitamin C deficiency in a university teaching hospital.
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OBJECTIVE
There is almost no information regarding the vitamin C status of patients treated in Canadian and American hospitals. We determined the prevalence and predictors of vitamin C deficiency in patients hospitalized on the acute-care wards of a Canadian teaching hospital, and tracked their
Vitamin C deficiency in cancer patients.
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OBJECTIVE
To assess the prevalence of vitamin C deficiency within a group of hospice patients. To assess the relationship between plasma vitamin C, dietary intake and subsequent survival.
METHODS
Patients with advanced cancer were recruited from a large hospice. Data were collected on demographic
Scurvy results in decreased collagen synthesis and bone density in the guinea pig animal model.
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The effect of severe ascorbic acid deficiency on bone remodeling and collagen synthesis was evaluated in a 21 day experiment, using the scorbutic guinea pig model. Animals (n = 6-7/group) were assigned to one of three groups: scorbutic, pair-fed ascorbic acid-replete, or ad libitum ascorbic
Musculoskeletal manifestations of scurvy.
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Scurvy occurs in individuals who eat inadequate amounts of fresh fruit or vegetables, often because of dietary imbalances related to advanced age or homelessness. Asthenia, vascular purpura, bleeding, and gum abnormalities are the main symptoms. In 80% of cases, the manifestations of scurvy include
Is leucocyte ascorbic acid an unreliable estimate of vitamin C deficiency?
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Leucocyte ascorbic acid levels failed to identify six of seven elderly patients shown to be deficient on an oral vitamin C saturation test. Compared to those with a normal saturation test, patients judged deficient had lower levels for triceps skinfold thickness, mean arm muscle circumference and
Ascorbic acid deficiency changes hepatic gene expression of acute phase proteins in scurvy-prone ODS rats.
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The ODS rat (genotype od/od), which has a hereditary defect in ascorbic acid biosynthesis, was used to investigate the effects of ascorbic acid deficiency on the hepatic gene expression of both the positive acute phase proteins, haptoglobin and alpha1-acid glycoprotein, and the negative acute phase
Vitamin C deficiency exacerbates diabetic glomerular injury through activation of transforming growth factor-β signaling.
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The hyperglycemia and hyperoxidation that characterize diabetes lead to reduced vitamin C (VC) in diabetic humans and experimentally diabetic animals. Herein, we access the effects of VC deficiency on the diabetic kidney injury and explore the underlying mechanism.
l-gulonolactone oxidase
Epidemiological survey of vitamin deficiencies in older Thai adults: implications for national policy planning.
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OBJECTIVE
To examine the prevalence and risk factors of vitamin deficiencies among older Thai adults.
METHODS
The cross-sectional study was conducted in four rural communities, one from each of the four main regions of Thailand. In total, 2336 subjects aged 60 years and over were recruited.
Nutritional status of renal transplant patients.
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OBJECTIVE
To assess the effect of renal transplantation on the nutritional status of patients.
METHODS
Prospective descriptive study.
METHODS
Renal Transplant Clinic at Tygerberg Hospital, Western Cape.
METHODS
Fifty-eight renal transplant patients from Tygerberg Hospital were enrolled in the study.
Nutritional status, dietary intake and serum levels of vitamin C upon diagnosis of cancer in children and adolescents.
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BACKGROUND
The prevalence of malnutrition upon diagnosis, together with reduced food intake secondary to disease and treatment, make the periodic assessment of nutritional status (including the intake of antioxidant nutrients) of considerable importance to the follow up of patients with
Broad-Ranging Nutritional Deficiencies Predict Amputation in Diabetic Foot Ulcers.
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Diabetic foot ulcers present across the spectrum of nonhealing wounds, be it acute or many months duration. There is developing literature highlighting that despite this group having high caloric intake, they often lack the micronutrients essential for wound healing. This study reports a
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