stemona/antifungik

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Implementation of bio-fungicides and seed treatment in organic rice cv. KDML 105 farming.

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This study was aimed to evaluate the several chemical compounds of relatively composite structure with antifungal activity from Thai local medical plants. The antifungal activity of Stemona curtisii HK. f., Stemona tuberose L., Acorus calamus L., Eugenia caryophyllus, Memmea siamensis Kost. and an

Antifungal stilbenoids from Stemona japonica.

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Three new dihydrostilbenes, stilbostemins P-R (1-3), and a new dihydrophenanthrene, stemanthrene G (4), were isolated from the roots of Stemona japonica together with three known bibenzyls, 3,5-dihydroxy-2'-methoxy bibenzyl (5), 3,3'-dihydroxy-2,5'-dimethoxy bibenzyl (6), and

Dihydrophenanthrenes and other antifungal stilbenoids from Stemona cf. pierrei.

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Three new dihydrophenanthrenes, stemanthrenes A-C, along with the new dihydrostilbene stilbostemin G were isolated and identified from the underground parts of Stemona cf. pierrei together with the known pinosylvin, 4'-methylpinosylvin, dihydropinosylvin, stilbostemins B, D, and E as well as the

The therapeutic effects of tuberostemonine against cigarette smoke-induced acute lung inflammation in mice.

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Chronic obstructive pulmonary disease (COPD) is mainly caused by cigarette smoking and is characterized by the destruction of lung parenchyma, structural alterations of the small airways, and systemic inflammation. Tuberostemonine (TS) is an alkaloid-type phytochemical from Stemona tuberosa. In the

Antifungal stilbenoids from Stemona collinsae.

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Fifteen new stilbenoids including 11 phenylbenzofurans, the stemofurans A-K (1-11), and four dihydrostilbenes, the stilbostemins A (15), C (17), E (19), and F (20), were isolated and identified from a methanolic extract of Stemona collinsae roots together with five known derivatives, the stilbenes

Phytochemical studies on Stemona aphylla: isolation of a new stemofoline alkaloid and six new stemofurans.

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A new stemofoline alkaloid, (2'S)-hydroxy-(11S,12R)-dihydrostemofoline (3), new stemofurans M-R (8-13), and known compounds stemofoline (1), (2'S)-hydroxystemofoline (2), stemofuran E (4), stemofuran F (5), stemofuran J (6), and stilbostemin F (7) have been isolated from the root extracts of Stemona

The effects of the standardized herbal formula PM014 on pulmonary inflammation and airway responsiveness in a murine model of cockroach allergen-induced asthma.

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BACKGROUND PM014 is a modified form of the Chung-Sang-Bo-Ha-Tang (CSBHT) herbal formula that has been used to treat chronic pulmonary diseases in Korea for centuries. Previously, we developed a formulation of PM014 based on a series of in vitro and in vivo screening efforts that comprises seven

[Difference in effect between asthma-based mouse model and Stemona tuberosa extracts].

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In this study, OVA-induced asthma mice was taken as the model, and orally administered with different concentration of ethanol extracts of crude and processed Stemona tuberosa, in order to determine the cytokine level released from Th1 and Th2 in splenocytes. RT-PCR was carried out to determine the

Phytochemical investigations of Stemona curtisii and synthetic studies on stemocurtisine alkaloids.

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The isolation of two new Stemona alkaloids, 1-hydroxyprotostemonine and stemocurtisine N-oxide, and a new benzofuran, stemofuran L, from the root extracts of Stemona curtisii is reported. The major known alkaloids from this plant extract, stemocurtisine, stemocurtisinol, and oxyprotostemonine, were

Tuberostemonine N, an active compound isolated from Stemona tuberosa, suppresses cigarette smoke-induced sub-acute lung inflammation in mice.

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OBJECTIVE Our previous study demonstrated that a Stemona tuberosa extract had significant effects on cigarette smoking (CS)-induced lung inflammation in mice. The present study evaluated the potential of tuberostemonine N (T.N) to prevent airway inflammation and suppress airway responses in a

Inhibitory effects of Stemona tuberosa on lung inflammation in a subacute cigarette smoke-induced mouse model.

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BACKGROUND Stemona tuberosa has long been used in Korean and Chinese medicine to ameliorate various lung diseases such as pneumonia and bronchitis. However, it has not yet been proven that Stemona tuberosa has positive effects on lung inflammation. METHODS Stemona tuberosa extract (ST) was orally

The diversity of Stemona stilbenoids as a result of storage and fungal infection.

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In relation to their biogenetic origin, 68 Stemona stilbenoids have been grouped into four structural types and are listed in order of increasing substitution pattern. Besides different hydroxylations and methoxylations, the rare C-methylations of the aromatic rings represent a typical chemical

The traditional uses, phytochemistry, and pharmacology of Stemona species: A review

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Ethnopharmacological relevance: Plants of genus Stemona (Stemonaceae) have long been used locally and traditionally in many South and East Asia counties to relieve cough, dispel phlegm, prevent asthma, control pests, diminish inflammation

Neotuberostemonine inhibits osteoclastogenesis via blockade of NF-κB pathway.

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Osteoporosis has been attributed to low bone mass arising from cellular communications between bone formation and bone resorption. Osteoclastogenesis is induced by M-CSF and RANKL in hematopoietic lineage cells. Once RANK/RANKL complex is formed, TRAF6 is recruited and triggers the activation of

Protostemonine effectively attenuates lipopolysaccharide-induced acute lung injury in mice.

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Protostemonine (PSN) is the main anti-inflammatory alkaloid extracted from the roots of Stemona sessilifolia (known as "Baibu" in traditional Chinese medicine). Here, we reported the inhibitory effects of PSN on lipopolysaccharide (LPS)-induced macrophage activation in vitro and LPS-induced acute

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