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testicular neoplasms/hypoxia
Veza se sprema u međuspremnik
8 rezultatima
Successful management of a patient with radiological presentation of choriocarcinoma syndrome before induction chemotherapy.
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Prijava Registriraj se
Choriocarcinoma syndrome is a life-threatening lysis syndrome caused by blood vessel rupture and subsequent tumor bleeding. We describe a case of pretreatment choriocarcinoma syndrome that developed in a 27-year-old man. He underwent a high orchiectomy at a local hospital and was diagnosed with
Prognostic value of intratumoral carbonic anhydrase IX expression in testicular germ cell tumors.
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Prijava Registriraj se
Testicular germ cell tumors (TGCTs) represent a highly curable malignancy, however a small proportion of patients fails to be cured with cisplatin-based chemotherapy. Carbonic anhydrase IX (CA IX) is upregulated by hypoxia in several cancer types and correlates with a poor prognosis. The present
Treatment of spontaneous tumours by temporary local ligation. A comparative study in dogs.
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Prijava Registriraj se
Previous work in some human cases and in laboratory animals has indicated that temporary local ligation of spontaneous tumours has a selective destructive effect on these tumours, with only temporary inflammation resulting in normal tissues. In the experiments described in this paper, 49 spontaneous
Large-dose bleomycin therapy and pulmonary toxicity. A possible role of prior radiotherapy.
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Prijava Registriraj se
Bleomycin sulfate pulmonary toxicity was encountered in nine of 101 patients receiving high-dose therapy for widespread testicular cancer. The pulmonary presentation was separable into two categories: (1) an early or minimal from with dyspnea on exertion, minimal roentgenographic findings, and
An unusual case of high altitude-like retinopathy caused by anemia and thrombocytopenia at recreational altitude.
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OBJECTIVE
To report an unusual presentation of high altitude-like retinopathy at recreational altitude after chemotherapy-induced anemia and thrombocytopenia.
METHODS
Case report.
RESULTS
A 43-year-old man undergoing chemotherapy for testicular cancer traveled to an altitude of 2,930 m and
Spermatogonial stem cells and progenitors are refractory to reprogramming to pluripotency by the transcription factors Oct3/4, c-Myc, Sox2 and Klf4.
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Prijava Registriraj se
The male germinal lineage, which is defined as unipotent, produces sperm through spermatogenesis. However, embryonic primordial germ cells and postnatal spermatogonial stem cells (SSCs) can change their fate and convert to pluripotency in culture when they are not controlled by the testicular
Stem cell factor induces HIF-1alpha at normoxia in hematopoietic cells.
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Prijava Registriraj se
Signaling by the receptor for stem cell factor (SCF), c-Kit, is of major importance for hematopoiesis, melanogenesis and reproduction, and the biological responses are commonly proliferation and cell survival. Thus, constitutive activation due to c-Kit mutations is involved in the pathogenesis of
Adult leydig cell tumors of the testis caused by germline fumarate hydratase mutations.
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Prijava Registriraj se
BACKGROUND
Leydig cell tumors (LCTs) are the most common non-germ-cell neoplasms of the testis. LCTs are often hormonally active and can result in precocious virilization or in adult feminization. We identified an LCT in an affected individual from a kindred with hereditary leiomyomatosis and renal
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