6 rezultatima
Basidiobolomycosis is a fungal infection caused mainly by Basidiobolus ranarum, a filamentous fungus of the order Entomophthorales and the family Basidiobolaceae. This infection typically involves the skin and soft tissue; however, visceral organ involvement has also been reported. Here, we report a
A 21-year-old woman suffered heatstroke and developed diarrhea while trekking across south Texas. The heatstroke was complicated by seizures, rhabdomyolysis, pneumonia, renal failure, and disseminated intravascular coagulation. The patient's stool and blood cultures grew Campylobacter jejuni. The
Gastrointestinal zygomycosis was diagnosed in 3 suckling pigs (10, 14, and 28 days old) with diarrhea that was unresponsive to treatment with broad-spectrum antibiotics. The 3 pigs were from separate farms, and littermates of the 3 pigs with similar clinical signs had died. At necropsy, 2 of the 3
Acute gastric zygomycosis (mucormycosis) was diagnosed in four 6- to 7-day-old pigs with large venous infarcts in the gastric fundus. Two pigs were from one farm where several dams had developed fever at parturition and most of their litters had died. The other 2 pigs, from separate farms, had
OBJECTIVE
To summarize the published clinical data on posaconazole, critically review the New Drug Application data submitted to the Food and Drug Administration, and provide information critical for evaluation and formulary positioning.
METHODS
Reported investigations were identified from MEDLINE
BACKGROUND
The incidence of invasive fungal infections (IFIs) caused by opportunistic filamentous molds is increasing, along with emerging fungal resistance. Posaconazole, a structural analogue of itraconazole that was approved for marketing in the United States in 2006, appears to be a promising